1599446-48-6Relevant articles and documents
Developing the scope of o→c aryl migrations: Exploring amide substrates as potential precursors for asymmetric reactions
Ameen, Dana,Snape, Timothy J.
, p. 1925 - 1934 (2014/04/03)
A new and mild method for the production of diasteromerically enriched α-aryl carbonyl compounds has been achieved. Although only modest diastereoselectivies are observed, they demonstrate the potential of the method for further optimisation. It also appears that reactions that proceed through a five-membered spirocyclic transition state rearrange, whereas those proceeding through a six-membered transition state do not, but stop at the diaryl ether stage.
