1599460-38-4

Basic information

• Product Name: bis(3,5,7,3',4'-penta-O-benzyl-8-catechinyl)methanone
• Synonyms: bis(3,5,7,3',4'-penta-O-benzyl-8-catechinyl)methanone
• CAS NO: 1599460-38-4
• Molecular Weight: 1507.79
• Mol File: 1599460-38-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: bis(3,5,7,3',4'-penta-O-benzyl-8-catechinyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: bis(3,5,7,3',4'-penta-O-benzyl-8-catechinyl)methanone(1599460-38-4)
• EPA Substance Registry System: bis(3,5,7,3',4'-penta-O-benzyl-8-catechinyl)methanone(1599460-38-4)

Safety Data

• Hazardous Substances Data: 1599460-38-4(Hazardous Substances Data)

Upstream product

• 407-25-0 trifluoroacetic anhydride 
• 85443-49-8 (2R,3S)-3,5,7-tris(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)chroman 
• 89385-96-6 3,5,7,3',4'-penta-O-benzyl-8-carboxycatechin 

Downstream Products

• 1599460-40-8 bis(3,5,7,3',4'-Penta-O-benzyl-8-catechinyl)methane 

Relevant articles and documents

Total synthesis of (-)-bis-8,8′-catechinylmethane isolated from cocoa liquor

An efficient synthesis of bis-8,8′-catechinylmethane, a dimeric flavanol linked through a methylene bridge, is described. Our strategy involved a regioselective coupling via a trifluoroacetic anhydride condensation reaction followed by ketone reduction to the methylene employing new conditions (lithium aluminum hydride and hexafluorophosphoric acid).