15995-42-3Relevant articles and documents
Modular syntheses of multidentate ligands with variable N-donors: Applications to tri- and tetracopper(i) complexes
Brown, Eric C.,Johnson, Brandon,Palavicini, Sara,Kucera, Benjamin E.,Casella, Luigi,Tolman, William B.
, p. 3035 - 3042 (2007)
A general method for the preparation of multidentate ligands comprised of a multi-imine platform derived from 1,1,1-tris(aminomethyl)ethane or tris(aminoethyl)amine connected to bi- and tridentate N-donor chelates has been developed. The feasibility of the method has been demonstrated through the synthesis and characterization of a large set of these ligand types. Complexation to Cu(i) was accomplished for several cases, yielding tri- and tetracopper(i) complexes that have been characterized in solution by NMR spectroscopy and conductivity, and in the solid state by elemental analysis, mass spectrometry, and/or X-ray crystallography. These complexes are potentially useful for modeling multicopper protein active sites. The Royal Society of Chemistry.
Spin Crossover in a Hexaamineiron(II) Complex: Experimental Confirmation of a Computational Prediction
Bernhardt, Paul V.,Bilyj, Jessica K.,Brosius, Victor,Chernyshov, Dmitry,Deeth, Robert J.,Foscato, Marco,Jensen, Vidar R.,Mertes, Nicole,Riley, Mark J.,T?rnroos, Karl W.
, p. 5082 - 5085 (2018)
Single crystal structural analysis of [FeII(tame)2]Cl2?MeOH (tame=1,1,1-tris(aminomethyl)ethane) as a function of temperature reveals a smooth crossover between a high temperature high-spin octahedral d6 state and a low temperature low-spin ground state without change of the symmetry of the crystal structure. The temperature at which the high and low spin states are present in equal proportions is T1/2=140 K. Single crystal, variable-temperature optical spectroscopy of [FeII(tame)2]Cl2?MeOH is consistent with this change in electronic ground state. These experimental results confirm the spin activity predicted for [FeII(tame)2]2+ during its de novo artificial evolution design as a spin-crossover complex [Chem. Inf. Model. 2015, 55, 1844], offering the first experimental validation of a functional transition-metal complex predicted by such in silico molecular design methods. Additional quantum chemical calculations offer, together with the crystal structure analysis, insight into the role of spin-passive structural components. A thermodynamic analysis based on an Ising-like mean field model (Slichter–Drickammer approximation) provides estimates of the enthalpy, entropy and cooperativity of the crossover between the high and low spin states.
Design, synthesis and photophysical properties of 8-hydroxyquinoline-functionalized tripodal molecular switch as a highly selective sequential pH sensor in aqueous solution
Akbar, Rifat,Baral, Minati,Kanungo
, p. 16207 - 16222 (2015)
The development and photophysical properties of a biomimetic analogue of microbial siderophore from quinolobactin have been described. The putative analogue, 5,5′-(2(((8-hydroxyquinolin-5-yl)methylamino)methyl)2-methylpropane-1,3-diyl)-bis(azanediyl)-bis(methylene)diquinolin-8-ol (TAME5OX), was synthesized with three bidentate 8-hydroxyquinoline (8HQ) groups, connected to a 1,1,1-tris(aminomethyl)ethane framework, and was selected for its potential applications in chemical and biological fields. A combination of absorption and emission spectrophotometry, potentiometry, electrospray mass spectrometry, NMR, IR and theoretical investigation was used to fully characterize TAME5OX. The intense fluorescence from TAME5OX is quenched intermittently under acidic and basic conditions due to the photoinduced intramolecular electron transfer from excited N-pyridyl to hydroxyl moiety of 8HQ units. This renders the ligand an OFF-ON-OFF type of pH-dependent fluorescent sensor. DFT was employed for optimization and evaluation of vibrational modes, excitation and emission properties of the protonated, neutral, deprotonated states of the analogue. Anomalous enhancement observed in the fluorescence spectra of the neutral form of the sensor can be attributed to subtle structural differences from its cationic and anionic forms. Plausible explanations for low fluorescence of the acidic as well as basic form are provided. This journal is
Cation-Exchange Chromatography and Selective Complexation in hte Isolation of Branched Acyclic Polyamines: Syntheses of Ethylidenetris(methanamine) , 2,2-Bis(aminomethyl)propan-1-ol , 4,4',4''-Ethylidenetris(3-azabutan-1-amine) and...
Geue, Rodney J.,Searle, Graeme H.
, p. 927 - 935 (1983)
Large-scale syntheses of ethylidynetris(methanamine) (tame), 2,2-bis(aminomethyl)propan-1-ol (hmmp), 4,4'-4'-ethylidynetris(3-azabutan-1-amine) (sen) and 5,5'-5'-ethylidynetris(4-azapentan-1-amine) (stn) are described.The pure hydrochloride salts of tame,
