1600527-27-2

Basic information

• Product Name: 2-(3-fluorophenethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• Synonyms: 2-(3-fluorophenethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 1600527-27-2
• Molecular Weight: 250.121
• Mol File: 1600527-27-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-(3-fluorophenethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-fluorophenethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1600527-27-2)
• EPA Substance Registry System: 2-(3-fluorophenethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1600527-27-2)

Safety Data

• Hazardous Substances Data: 1600527-27-2(Hazardous Substances Data)

Upstream product

• 25017-13-4 1-(2-bromoethyl)-3-fluorobenzene 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 350-51-6 3-fluorostyrene 
• 73183-34-3 bis(pinacol)diborane 
• 2561-17-3 1-ethynyl-3-fluoro-benzene 

Relevant articles and documents

Chromium-Catalyzed Borylative Coupling of Aliphatic Bromides with Pinacolborane by Hydrogen Evolution

The chromium-catalyzed borylative coupling between aliphatic bromides and pinacolborane (HBpin) is described. This reaction was promoted by low-cost and bench-stable CrCl3as a precatalyst combined with 4,4′-di-tert-butyl-2,2′-dipyridyl and aluminum, presenting a rare example of using HBpin as a borane reagent by coupling with alkyl bromides in forming borylated alkanes. Mechanistic studies indicate that aluminum plays important roles in the formation of reactive Cr species and aliphatic radicals, which lead to (alkyl)Cr by reaction with HBpin to give the products.

Manganese-Catalyzed Hydroboration of Terminal Olefins and Metal-Dependent Selectivity in Internal Olefin Isomerization-Hydroboration

In the past decade, the use of earth-abundant metals in homogeneous catalysis has flourished. In particular, metals such as cobalt and iron have been used extensively in reductive transformations including hydrogenation, hydroboration, and hydrosilylation

Lewis acid catalysis: Regioselective hydroboration of alkynes and alkenes promoted by scandium triflate

The first commercially available scandium-catalysed selective hydroboration of alkynes and alkenes with HBpin (pin = OC-Me2CMe2O) in the presence of a catalytic amount of NaHBEt3 has been developed. This protocol can be applicable to a wide range of substrates including aromatic, aliphatic with cyclic and acyclic side chains, and heteroaryl systems with broad functional-group compatibility. Mechanistic studies revealed that the reaction occurs in a syn fashion via the σ-bond metathesis between the alkenyl scandium species and HBpin.