16015-12-6

Basic information

• Product Name: 2H-Pyran, 3,4-dihydro-2-phenyl-
• CAS NO: 16015-12-6
• Molecular Formula: C11H12O
• Molecular Weight: 160.216
• Mol File: 16015-12-6.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 2H-Pyran, 3,4-dihydro-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran, 3,4-dihydro-2-phenyl-(16015-12-6)
• EPA Substance Registry System: 2H-Pyran, 3,4-dihydro-2-phenyl-(16015-12-6)

Safety Data

• Hazardous Substances Data: 16015-12-6(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 123-31-9 hydroquinone 
• 107-02-8 acrolein 
• 98088-48-3 1-(allyloxy)-1-phenylbut-3-ene 
• 61201-27-2 1-phenylpenta-4,5-dien-1-ol 
• 763-32-6 2-methyl-1-buten-4-ol 
• 100-52-7 benzaldehyde 
• 110-87-2 3,4-dihydro-2H-pyran 
• 108-90-7 chlorobenzene 
• 108-86-1 bromobenzene 
• 103-71-9 phenyl isocyanate 
• 120749-57-7 cis-2-(benzenesulphonyl)tetrahydro-6-methoxy-2H-pyran 
• 120749-57-7 trans-2-(benzenesulphonyl)tetrahydro-6-methoxy-2H-pyran 
• 31357-97-8 trans-tetrahydro-2-methoxy-6-phenyl-2H-pyran 

Downstream Products

• 55066-48-3 3-methyl-5-phenylpentan-1-ol 
• 1501-05-9 5-oxo-5-phenylvaleric acid 
• 322764-79-4 5-hydroxy-5-phenyl-valeraldehyde 
• 74457-58-2 4-oxo-2-phenyl-butyric acid 
• 2051-95-8 succinylbenzene 

Relevant articles and documents

A new synthesis of highly functionalized cyclohexenes via a vinylogous Ferrier-Petasis cyclization reaction

Research on the O→C rearrangement reaction shows that alkoxydienes undergo a smooth rearrangement in a vinylogous manner with a catalytic amount of titanium (IV) chloride, which leads to highly substituted cyclohexenes a particularly useful starting mater

Preparation method of 3-methyl-5-phenyl-amyl alcohol

The invention provides a preparation method of 3-methyl-5-phenyl-amyl alcohol. The preparation method comprises the following steps of phenyl-dihydropyran preparation, wherein the weight ratio of solid acid to 3-methyl-3-butenol is 1:(100-5,000), the weight ratio of xylene to 3-methyl-3-butenol is (0.5-2.0):1.0, and the weight ratio of benzaldehyde to 3-methyl-3-butenol is (1.2-3.0):1.0; a hydrogenation reaction, wherein the hydrogenation reaction is conducted for 1 h to 15 h at the temperature of 45 DEG C to 150 DEG C under the pressure of 0.3 MPa to 2.5 MPa. According to the preparation method, phenyl-dihydropyran is efficiently generated by mainly adopting a vacuum tower type reactor and a negative-pressure cyclization technology; a cocatalyst is added in the hydrogenation reaction, and therefore it is guaranteed that the conversion rate and the selectivity are high, the catalyst is recycled for multiple batches and is low in cost, the yield of the final product is high, and industrialized production can be achieved.

Ruthenium-catalyzed olefin metathesis double-bond isomerization sequence

A novel ruthenium-catalyzed tandem ring-closing metathesis (RCM) double-bond isomerization reaction is described in this paper. The utility of this method for the efficient syntheses of five-, six-, and seven-membered cyclic enol ethers is demonstrated. It relies on the conversion of a metathesis-active ruthenium carbene species to an isomerization-active ruthenium-hydride species in situ. This conversion is achieved by using various additives. Scope and limitations of the different protocols are discussed, and some mechanistic considerations based on 31P and 1H NMR spectroscopic studies are presented.