1603-46-9Relevant articles and documents
Oxidation of Flavonols using lead(IV) acetate in acidic methanol
Kumar,Singh
, p. 1333 - 1337 (2007/10/02)
Oxidation of Flavonols (1a-h) and 6-propionylflavonols (1i-j) to 2,3-dimethoxy-3-hydroxyflavanones (2a-h) and 2,3-dimethoxy-3-hydroxyflavanones (2i-j), respectively using lead(IV) acetate in methanol in presence of perchloric acid and the mechanism of this transformation has been described.
HYPERVALENT IODINE OXIDATION OF FLAVONOLS USING BENZENE IN METHANOL
Moriarty, Robert M.,Prakash, Om,Musallam, Hikmat A.,Mahesh, Vijendra K.
, p. 1641 - 1645 (2007/10/02)
Hypervalent iodine oxidation of various flavonols (1a-1f) and α-naphthoflavonol (3) using benzene (HTIB) in methanol leads to the formation of 2,3-dimethoxy-3-hydroxyflavanones (2a-2f) and 2,3-dimethoxy-3-hydroxy-α-naphthoflavanone (4) respectively.HTIB resembles periodic acid in its oxidative behavior towards flavonols.
Reactions of Flav-2-enes and Flav-2-en-4-ones (Flavones)
Bird, T. Geoffrey C.,Brown, Ben R.,Stuart, Ian A.,Tyrrell, William R.
, p. 1831 - 1846 (2007/10/02)
Flav-2-enes, flavones, and 3-alkyl ethers of flavonols add alcohols and carboxylic acids in the presence of N-bromosuccinimide to give 2-alkoxy- and 2-acyloxy-3-bromoflavans which provide routes to cis-3-bromoflavans by reduction and to 3,4-diols by elimination and reaction with osmium tetraoxide.The 2-acyloxyflavans react with alcohols yielding 2-alkoxyflavans.Flavonols react with N-bromosuccinimide and alcohols to give bromine-free hemiacetals, the known 2,3-dialkoxy-3-hydroxyflavanones.