160334-26-9

Basic information

• Product Name: (S)-2-(3-benzoylphenyl)-N-phenylpropanamide
• Synonyms: (S)-2-(3-benzoylphenyl)-N-phenylpropanamide
• CAS NO: 160334-26-9
• Molecular Weight: 329.398
• Mol File: 160334-26-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-2-(3-benzoylphenyl)-N-phenylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(3-benzoylphenyl)-N-phenylpropanamide(160334-26-9)
• EPA Substance Registry System: (S)-2-(3-benzoylphenyl)-N-phenylpropanamide(160334-26-9)

Safety Data

• Hazardous Substances Data: 160334-26-9(Hazardous Substances Data)

Upstream product

• 22161-81-5 S-ketoprofen 
• 62-53-3 aniline 
• 201230-82-2 carbon monoxide 
• 63444-57-5 3-benzoylstyrene 

Relevant articles and documents

Asymmetric Markovnikov Hydroaminocarbonylation of Alkenes Enabled by Palladium-Monodentate Phosphoramidite Catalysis

A palladium-catalyzed asymmetric Markovnikov hydroaminocarbonylation of alkenes with anilines has been developed for the atom-economical synthesis of 2-substituted propanamides bearing an α-stereocenter. A novel phosphoramidite ligand L16 was discovered which exhibited very high reactivity and selectivity in the reaction. This asymmetric Markovnikov hydroaminocarbonylation employs readily available starting materials and tolerates a wide range of functional groups, thus providing a facile and straightforward method for the regio- and enantioselective synthesis of 2-substituted propanamides under ambient conditions. Mechanistic studies revealed that the reaction proceeds through a palladium hydride pathway.