160450-12-4 Usage
General Description
N-BOC-3-AMINO-4-CHLOROBENZOIC ACID is a chemical compound with a molecular formula C12H13ClNO4. It is a derivative of 3-amino-4-chlorobenzoic acid that has a tert-butoxycarbonyl (BOC) protecting group attached to the amino group. N-BOC-3-AMINO-4-CHLOROBENZOIC ACID is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a reagent in organic chemistry reactions, particularly in the formation of amide bonds. N-BOC-3-AMINO-4-CHLOROBENZOIC ACID is a white to off-white solid that is stable under normal conditions, and it is important to handle it with proper safety precautions as it can be harmful if ingested or inhaled.
Check Digit Verification of cas no
The CAS Registry Mumber 160450-12-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,4,5 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 160450-12:
(8*1)+(7*6)+(6*0)+(5*4)+(4*5)+(3*0)+(2*1)+(1*2)=94
94 % 10 = 4
So 160450-12-4 is a valid CAS Registry Number.
160450-12-4Relevant articles and documents
Design and synthesis of α-ketoamides as cathepsin s inhibitors with potential applications against tumor invasion and angiogenesis
Chen, Jo-Chun,Uang, Biing-Jiun,Lyu, Ping-Chiang,Chang, Jang-Yang,Liu, Ko-Jiunn,Kuo, Ching-Chuan,Hsieh, Hsing-Pang,Wang, Hsin-Chieh,Cheng, Chao-Sheng,Chang, Yi-Hsun,Chang, Margaret Dah-Tsyr,Chang, Wun-Shaing Wayne,Lin, Chun-Cheng
scheme or table, p. 4545 - 4549 (2010/08/19)
A series of small molecules bearing an α-ketoamide warhead were synthesized and evaluated for their ability to inhibit cathepsin S, a key proteolytic enzyme upregulated in many cancers during tumor progression and metastasis. Most of the synthetic compounds were noncytotoxic, but several robustly inhibited cathepsin S (IC50 10 nM) and potently suppressed cell migration, invasion, and capillary tube formation. These results highlight the potential of α-ketoamide therapy for preventing or delaying cancer spread.
