160450-13-5

Basic information

• Product Name: Benzoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-
• CAS NO: 160450-13-5
• Molecular Formula: C12H15NO5
• Molecular Weight: 253.255
• Mol File: 160450-13-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-(160450-13-5)
• EPA Substance Registry System: Benzoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-(160450-13-5)

Safety Data

• Hazardous Substances Data: 160450-13-5(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 2374-03-0 4-aminosalicylic acid 

Downstream Products

• 183968-79-8 4-amino-3-hydroxy-benzoic acid butyl ester 

Relevant articles and documents

B-5354a, b and c, new sphingosine kinase inhibitors, produced by a marine bacterium; taxonomy, fermentation, isolation, physico-chemical properties and structure determination

In the course of our screening for inhibitors of sphingosine kinase, we found a series of active compounds in a culture broth of a novel marine bacterium, SANK 71896. The structures of the compounds, named B-5354a, b and c, were elucidated by a combination of spectroscopic analyses to be new esters of 4-amino-3-hydroxybenzoic acid with long-chain unsaturated alcohols. B-5354a, b and c inhibit sphingosine kinase activity with IC50 values of 21, 58 and 38 υM, respectively.