160521-72-2 Usage
Description
BW 723C86 is a selective 5-HT2B receptor agonist, which is a type of compound that interacts with the 5-HT2B receptor, a subtype of the serotonin receptor. This interaction has potential therapeutic applications in various conditions.
Uses
Used in Central Nervous System (CNS) Disorders:
BW 723C86 is used as a therapeutic agent for the treatment of certain CNS disorders. Its agonistic action on the 5-HT2B receptor can help alleviate symptoms and improve the quality of life for patients.
Used in Epilepsy Treatment:
BW 723C86 is used as an anticonvulsant medication for the treatment of epilepsy. By targeting the 5-HT2B receptor, it may help to reduce the frequency and severity of seizures in patients.
Used in Migraine Treatment:
BW 723C86 is used as a prophylactic treatment for migraines. Its agonistic effect on the 5-HT2B receptor may help to prevent or reduce the occurrence of migraine attacks.
Used in Feeding Disorders:
BW 723C86 is used as a treatment option for individuals with feeding disorders. Its interaction with the 5-HT2B receptor may help to regulate appetite and improve eating behaviors in affected patients.
Biological Activity
Selective 5-HT 2B receptor agonist.
Biochem/physiol Actions
5-HT2B serotonin receptor agonist.
references
[1]. kennett ga, bright f, trail b, et al. effects of the 5-ht2b receptor agonist, bw 723c86, on three rat models of anxiety. br j pharmacol, 1996, 117(7): 1443-1448.[2]. dergacheva o, wang x, kamendi h, et al. 5ht2 receptor activation facilitates p2x receptor mediated excitatory neurotransmission to cardiac vagal neurons in the nucleus ambiguus. neuropharmacology, 2008, 54(7): 1095-1102. [3]. kennett ga, trail b, bright f. anxiolytic-like actions of bw 723c86 in the rat vogel conflict test are 5-ht2b receptor mediated. neuropharmacology, 1998, 37(12): 1603-1610.[4]. urtikova n, berson n, van steenwinckel j, et al. antinociceptive effect of peripheral serotonin 5-ht2b receptor activation on neuropathic pain. pain, 2012, 153(6): 1320-1331.
Check Digit Verification of cas no
The CAS Registry Mumber 160521-72-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,5,2 and 1 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 160521-72:
(8*1)+(7*6)+(6*0)+(5*5)+(4*2)+(3*1)+(2*7)+(1*2)=102
102 % 10 = 2
So 160521-72-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H18N2OS.ClH/c1-11(17)7-12-9-18-16-5-4-13(8-15(12)16)19-10-14-3-2-6-20-14;/h2-6,8-9,11,18H,7,10,17H2,1H3;1H
