1605294-33-4

Basic information

• Product Name: 5-(3,4-dihydroquinolin-1(2H)-yl)-5-methyl-3-phenylhexan-3-ol
• Synonyms: 5-(3,4-dihydroquinolin-1(2H)-yl)-5-methyl-3-phenylhexan-3-ol
• CAS NO: 1605294-33-4
• Molecular Weight: 323.478
• Mol File: 1605294-33-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(3,4-dihydroquinolin-1(2H)-yl)-5-methyl-3-phenylhexan-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3,4-dihydroquinolin-1(2H)-yl)-5-methyl-3-phenylhexan-3-ol(1605294-33-4)
• EPA Substance Registry System: 5-(3,4-dihydroquinolin-1(2H)-yl)-5-methyl-3-phenylhexan-3-ol(1605294-33-4)

Safety Data

• Hazardous Substances Data: 1605294-33-4(Hazardous Substances Data)

Upstream product

• 1605294-24-3 3-(3,4-dihydroquinolin-1(2H)-yl)-3-methylbutanenitrile 
• 635-46-1 1,2,3,4-tetrahydroisoquinoline 
• 4786-24-7 3,3-dimethylacrylonitrile 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 1605294-42-5 1-ethyl-3,3-dimethyl-1-phenyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoline 

Relevant articles and documents

Modern friedel-crafts chemistry. part 37. efficient syntheses of some new julolidines via cyclialkylations of heteroaryl carbinols

A simple and convenient procedure for the synthesis of some novel alkyl-substituted and aryl-substituted julolidines is reported. Julolidines were smoothly synthesized in excellent isolated yields via Friedel-Crafts intramolecular alkylations of heteroarylalkanols in the presence of both Bronsted (PPA) and Lewis (AlCl3/CH3NO2) acid catalysts. The precursors alkanols, 1a, 1b, 1c, 1d, 1e, 1f, 1g, 1h, 1i, were readily prepared both by reaction of selectively synthesized carboxylic acid esters and ketones with different Grignard reagents and also by reduction of the synthesized ketones with LAH. A plausible carbocation mechanism is proposed to account for the results. The structures of the compounds are established using both spectral and analytical data.