16061-96-4

Basic information

• Product Name: O-benzoyl benzaldehyde oxime ester
• Synonyms: O-benzoyl benzaldehyde oxime ester
• CAS NO: 16061-96-4
• Molecular Weight: 225.247
• Mol File: 16061-96-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: O-benzoyl benzaldehyde oxime ester(CAS DataBase Reference)
• NIST Chemistry Reference: O-benzoyl benzaldehyde oxime ester(16061-96-4)
• EPA Substance Registry System: O-benzoyl benzaldehyde oxime ester(16061-96-4)

Safety Data

• Hazardous Substances Data: 16061-96-4(Hazardous Substances Data)

Upstream product

• 65-85-0 benzoic acid 
• 932-90-1 Benzaldoxime 
• 622-32-2 (Z)-benzaldehyde oxime 
• 98-88-4 benzoyl chloride 
• 100-52-7 benzaldehyde 
• 93-97-0 benzoic acid anhydride 
• 932-90-1 syn-benzaldehyde oxime 
• 110-86-1 pyridine 
• 2089-36-3 (E)-3,4-methylenedioxybenzaldehyde oxime 
• 121-44-8 triethylamine 
• 774-48-1 (diethoxymethyl)benzene 

Downstream Products

• 92-52-4 biphenyl 
• 16118-22-2 benzylidenamine 
• 18322-86-6 benzaldoxime benzoate 
• 100-47-0 benzonitrile 
• 1750-36-3 (E)-N-benzylidenebenzenamine 
• 28867-76-7 benzaldehyde benzylidenehydrazone 
• 33993-35-0 cis-benzylideneaniline 
• 71-43-2 benzene 
• 1278561-32-2 O-benzoyl-N-(1-phenylbut-3-enyl)hydroxylamine 
• 136411-10-4 5a-Phenyl-5aH,11H,13H-<1,3>benzothiazino<2,3-b><1,3>benzothiazin 
• 136411-11-5 6-Phenyl-6H,8H,13aH-<1,3>benzothiazino<4,3-b><1,3>benzothiazin 
• 100-52-7 benzaldehyde 
• 65-85-0 benzoic acid 

Relevant articles and documents

A convenient practical synthesis of alkyl and aryl oxime esters

A facile access to the synthesis of alkyl and aryl oxime esters of ketoximes and aldoximes in high yields (90-97%) is reported. The reactions were performed using N-[3-(methylamino)propyl]-N′-ethylcarbodiimide hydrochloride (EDCI) reagent in the presence of 4-(dimethylamino)pyridine (DMAP) as a catalyst at room temperature. The isolation and purification of products is very simple and in cases where product is solid, column chromatography is avoided. Georg Thieme Verlag Stuttgart New York.

NOVEL O-ACYLOXIME DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE

The present invention relates to novel O-acyloxime derivatives, a preparation method thereof and a pharmaceutical composition comprising the same for prevention and treatment of cardiovascular disease. The O-acyloxime derivatives according to the present invention may valuably be used for prevention and treatment of cardiovascular diseases such as hyperlipidemia, coronary arterial heart disease, atherosclerosis, and myocardial infarction caused by Lp-PLA2, because they have excellent inhibitory effect of Lp-PLA2.

(E)-Phenyl- and -heteroaryl-substituted O-benzoyl-(or acyl)oximes as lipoprotein-associated phospholipase A2 inhibitors

A series of (E)-phenyl- and -heteroaryl-substituted O-benzoyl- (or acyl)oximes 3a-n were synthesized for evaluating their human lipoprotein-associated phospholiphase A2 (Lp-PLA2) inhibitory activities. The less lipophilic derivatives 3a-c showed the most potent in vitro inhibitory activity on human Lp-PLA2.