1606126-38-8

Basic information

• Product Name: N-(4-(phenylethynyl)-1H-pyrazol-5-yl)acetamide
• Synonyms: N-(4-(phenylethynyl)-1H-pyrazol-5-yl)acetamide
• CAS NO: 1606126-38-8
• Molecular Weight: 225.25
• Mol File: 1606126-38-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(4-(phenylethynyl)-1H-pyrazol-5-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-(phenylethynyl)-1H-pyrazol-5-yl)acetamide(1606126-38-8)
• EPA Substance Registry System: N-(4-(phenylethynyl)-1H-pyrazol-5-yl)acetamide(1606126-38-8)

Safety Data

• Hazardous Substances Data: 1606126-38-8(Hazardous Substances Data)

Upstream product

• 90000-72-9 N-(2-acetyl-2H-pyrazol-3-yl)-acetamide 
• 1606126-37-7 N-(4-iodo-1H-pyrazol-5-yl)acetamide 
• 536-74-3 phenylacetylene 
• 3553-12-6 N-(1H-pyrazol-5-yl)acetamide 

Downstream Products

• 1606126-40-2 4-chloro-5-phenyl-1H-pyrazolo[3,4-c]pyridazine 
• 1606126-41-3 4-chloro-3-iodo-5-phenyl-1H-pyrazolo[3,4-c]pyridazine 
• 1606126-42-4 2-(4-chloro-3-iodo-5-phenyl-pyrazolo[3,4-c]pyridazin-1-yl)-1-[(3R)-3-fluoropyrrolidin-1-yl]ethanone 
• 1606126-23-1 2-[4-chloro-3-(4-fluorophenyl)-5-phenyl-pyrazolo[3,4-c]pyridazin-1-yl]-1-[(3R)-3-fluoropyrrolidin-1-yl]ethanone 
• 1606126-39-9 1-(1-ethoxyethyl)-4-(phenylethynyl)-1H-pyrazol-5-amine 
• 1608158-61-7 4-chloro-1-[2-[(3R)-3-fluoropyrrolidin-1-yl]ethyl]-3-iodo-5-phenylpyrazolo[3,4-c]pyridazine 
• 1608158-68-4 4-chloro-1-[2-(4-methylpiperazin-1-yl)ethyl]-5-phenyl-3-(2-pyridyl)pyrazolo[3,4-c]pyridazine 
• 1608159-64-3 3-iodo-1-[2-(4-methylpiperazin-1-yl)ethyl]-5-phenyl-pyrazolo[3,4-c]pyridazin-4-ol 
• 1608159-65-4 1-[2-(4-methylpiperazin-1-yl)ethyl]-5-phenyl-3-(pyrrolidin-1-yl)pyrazolo[3,4-c]pyridazin-4-ol 
• 1608158-69-5 4-chloro-1-[2-(4-methylpiperazin-1-yl)ethyl]-5-phenyl-3-pyrrolidin-1-yl-pyrazolo[3,4-c]pyridazine 
• 1608158-71-9 3-bromo-4-chloro-5-phenyl-1H-pyrazolo[3,4-c]pyridazine 
• 1608159-89-2 4-chloro-3-iodo-1-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine 
• 1606126-45-7 2-(4-chloro-3-iodo-5-phenyl-1H-pyrazolo[3,4-c]pyridazin-1-yl)-1-(pyrrolidin-1-yl)ethanone 
• 1606126-58-2 4-chloro-3-iodo-5-phenyl-1-((2-pyrrolidin-1-yl)ethyl)pyrazolo[3,4-c]pyridazine 

Relevant articles and documents

TREATMENT OF CANCER, INFLAMMATORY DISEASES AND AUTOIMMUNE DISEASES

The present disclosure relates to methods for the treatment or prevention of cancer, an inflammatory disease or an autoimmune disease with compounds of the invention as disclosed herein. The present disclosure also relates to methods for reducing risk of developing cancer, an inflammatory disease or an autoimmune disease with compounds of the invention as disclosed herein.

PYRAZOLOPYRIDAZINES AND METHODS FOR TREATING RETINAL-DEGERATIVE DISEASES AND HEARING LOSS ASSOCIATED WITH USHER SYNDROME

Compounds, compositions and methods for the treatment of retinal degenerative diseases, such as retinitis pigmentosa, Leber's congenital Amaurosis, Syndromic retinal degenerations, age-related macular degeneration and Usher Syndrome, and hearing loss associated with Usher Syndrome are described herein.