16071-25-3

Basic information

• Product Name: (S)-2-chlorobenzhydrol
• Synonyms: (S)-2-chlorobenzhydrol
• CAS NO: 16071-25-3
• Molecular Weight: 218.683
• Mol File: 16071-25-3.mol
• Article Data: 109

Chemical Properties

• CAS DataBase Reference: (S)-2-chlorobenzhydrol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-chlorobenzhydrol(16071-25-3)
• EPA Substance Registry System: (S)-2-chlorobenzhydrol(16071-25-3)

Safety Data

• Hazardous Substances Data: 16071-25-3(Hazardous Substances Data)

Usage

Description

(S)-2-chlorobenzhydrol, with the molecular formula C13H13ClO, is a chiral chemical compound that exists in two different forms as mirror images of each other. It is known for its unique structural and chiral properties, making it a valuable tool in the pharmaceutical industry for drug development and synthesis. Due to its potential toxicity if ingested or inhaled, it is crucial to handle (S)-2-chlorobenzhydrol with caution.

Uses

Used in Pharmaceutical Industry:
(S)-2-chlorobenzhydrol is used as a pharmaceutical intermediate for [application reason], leveraging its unique chiral properties to aid in the development and synthesis of various drugs.
Used as a Chiral Resolving Agent:
In the field of organic chemistry, (S)-2-chlorobenzhydrol is used as a chiral resolving agent for [application reason], facilitating the synthesis of other chiral compounds by providing a means to separate enantiomers and obtain the desired stereoisomer.

Upstream product

• 95950-06-4 1,2-bis-(2-chloro-phenyl)-1,2-diphenyl-ethane-1,2-diol 
• 108-38-3 m-xylene 
• 89-98-5 2-chloro-benzaldehyde 
• 5162-03-8 (2-chlorophenyl)(phenyl)methanone 
• 98-80-6 phenylboronic acid 
• 76847-21-7 2-Chlor-1-benzol 
• 17051-75-1 o-chlorophenyl phenyl sulfoxide 
• 100-52-7 benzaldehyde 
• 109-72-8 n-butyllithium 
• 64-17-5 ethanol 
• 6954-45-6 (2-chlorophenyl)(phenyl)methanol 
• 3900-89-8 2-Chlorobenzeneboronic acid 
• 65-85-0 benzoic acid 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 29921-41-3 (o-benzyl)chlorobenzene 
• 56961-47-8 2-chloro-benzhydryl chloride 
• 136908-26-4 1,1'-(1,1'-oxybis(ethane-1,1-diyl))dinaphthalene 
• 136908-13-9 1-{1-[(2-Chloro-phenyl)-phenyl-methoxy]-ethyl}-naphthalene 
• 136908-25-3 C₂₆H₂₀Cl₂O 
• 7732-18-5 water 
• 5576-53-4 (2-chloro-ethyl)-(2-chloro-benzhydryl)-ether 

Relevant articles and documents

Bio-inspired asymmetric aldehyde arylations catalyzed by rhodium-cyclodextrin self-inclusion complexes

Transition-metal catalysts are powerful tools for carbon-carbon bond-forming reactions that are difficult to achieve using native enzymes. Enzymes that exhibit inherent selectivities and reactivities through host-guest interactions have inspired widesprea

Manganese catalyzed asymmetric transfer hydrogenation of ketones

The asymmetric transfer hydrogenation (ATH) of a wide range of ketones catalyzed by manganese complex as well as chiral PxNy-type ligand under mild conditions was investigated. Using 2-propanol as hydrogen source, various ketones could be enantioselectively hydrogenated by combining cheap, readily available [MnBr(CO)5] with chiral, 22-membered macrocyclic ligand (R,R,R',R')-CyP2N4 (L5) with 2 mol% of catalyst loading, affording highly valuable chiral alcohols with up to 95% ee.

Chiral amino-pyridine-phosphine tridentate ligand, manganese complex, and preparation method and application thereof

The invention discloses a chiral amino-pyridine-phosphine tridentate ligand, a manganese complex, and a preparation method and application thereof. The chiral amino-pyridine-phosphine tridentate ligand is shown as a formula II, and the manganese complex of the chiral amino-pyridine-phosphine tridentate ligand can be used for efficiently catalyzing and hydrogenating ketone compounds to prepare chiral alcohol compounds in a high enantioselectivity mode. The chiral amino-pyridine-phosphine tridentate ligand and the manganese complex are simple in synthesis process, good in stability, high in catalytic activity and mild in reaction conditions.