160723-51-3

Basic information

• Product Name: methyl 4-oxo-4-(m-tolyl)butanoate
• Synonyms: methyl 4-oxo-4-(m-tolyl)butanoate
• CAS NO: 160723-51-3
• Molecular Weight: 206.241
• Mol File: 160723-51-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: methyl 4-oxo-4-(m-tolyl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-oxo-4-(m-tolyl)butanoate(160723-51-3)
• EPA Substance Registry System: methyl 4-oxo-4-(m-tolyl)butanoate(160723-51-3)

Safety Data

• Hazardous Substances Data: 160723-51-3(Hazardous Substances Data)

Upstream product

• 585-74-0 3-Methylacetophenone 
• 118540-56-0 4-(3-methylphenyl)-4-oxo-2-butenoic Acid 
• 591-17-3 meta-bromotoluene 
• 876656-42-7 methyl 4-hydroxy-4-(m-tolyl)but-2-ynoate 
• 292638-85-8 acrylic acid methyl ester 
• 620-23-5 m-tolyl aldehyde 
• 84498-31-7 3-dimethylamino-m-methylpropiophenone hydrochloride 
• 84498-32-8 3-oxo-3-m-tolyl-1-cyanopropane 
• 67-56-1 methanol 
• 59618-44-9 4-(3-methylphenyl)-4-oxobutanoic acid 
• 1490-25-1 succinic acid monomethylester chloride 

Downstream Products

• 30543-91-0 litseachromolaevane A 
• 228257-33-8 methyl 4-isopropyl-4-m-tolylbutyrate 
• 59618-44-9 4-(3-methylphenyl)-4-oxobutanoic acid 

Relevant articles and documents

Generation of Acyl Radicals from 1-Oxidoalkylidenechromium(0) Complexes by Treatment with Bis(2,2,6,6-tetramethyl-3,5-heptanedionato)copper(II) and Their Reactions with Olefins

Tetramethylammonium pentacarbonyl(1-oxidoalkylidene)chromium(0) complexes are oxidized with bis(2,2,6,6-tetramethyl-3,5-heptanedionato)copper(II) to generate acyl radicals which react electron-deficient olefins, giving intermolecular addition products.

MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF

The disclosure relates to compounds and pharmaceutical compositions capable of modulating the hydroxysteroid 17-beta dehydrogenase (HSD17B) family member proteins including inhibiting the HSD17B member proteins, e.g. HSD17B13. The disclosure further relates to methods of treating liver diseases, disorders, or conditions with the compounds and pharmaceutical compositions disclosed herein, in which the HSD17B family member protein plays a role.

Benzoyl radicals from (hetero)aromatic aldehydes. Decatungstate photocatalyzed synthesis of substituted aromatic ketones

Benzoyl radicals are generated directly from (hetero)aromatic aldehydes upon tetrabutylammonium decatungstate ((n-Bu4N)4W 10O32), TBADT) photocatalysis under mild conditions. In the presence of α,β-unsaturated e