1607830-35-2

Basic information

• Product Name: (R)-monobenzyl 3-(benzyloxymethoxy)glutarate
• Synonyms: (R)-monobenzyl 3-(benzyloxymethoxy)glutarate
• CAS NO: 1607830-35-2
• Molecular Weight: 358.391
• Mol File: 1607830-35-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-monobenzyl 3-(benzyloxymethoxy)glutarate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-monobenzyl 3-(benzyloxymethoxy)glutarate(1607830-35-2)
• EPA Substance Registry System: (R)-monobenzyl 3-(benzyloxymethoxy)glutarate(1607830-35-2)

Safety Data

• Hazardous Substances Data: 1607830-35-2(Hazardous Substances Data)

Upstream product

• 1607830-30-7 diethyl 3-(benzyloxymethyloxy)glutarate 
• 32328-03-3 diethyl 3-hydroxyglutarate 
• 1607830-32-9 3-(benzyloxymethoxy)glutaric anhydride 
• 100-51-6 benzyl alcohol 
• 1607830-31-8 3-(benzyloxymethoxy)glutaric acid 
• 3587-60-8 Benzyloxymethyl chloride 

Relevant articles and documents

Synthesis of GABOB and GABOB-based chiral units possessing distinct protecting groups

In addition to the varied biological activity of GABOB (4-amino-3- hydroxybutanoic acid), the structure of its protected derivatives makes them interesting chiral intermediates for the synthesis of more complex compounds. A stereoselective route to GABOB derivatives with three different protecting groups is presented, using anhydride desymmetrization as a chirality-inducing step. Selective removal of the protecting groups gave compounds with a free carboxylic acid or hydroxy group. Removal of all of the protecting groups allowed GABOB to be isolated in good yield and with excellent ee. A stereoselective route to GABOB (4-amino-3-hydroxybutanoic acid) derivatives with three different protecting groups is presented. Selective deprotection produced diprotected chiral building blocks with a free carboxylic acid or hydroxy group. Removal of all the protecting groups allowed GABOB to be isolated. Copyright