1607830-40-9

Basic information

• Product Name: (S)-3-(benzyloxy)-4-(benzyloxycarbonylamino)butyric acid
• Synonyms: (S)-3-(benzyloxy)-4-(benzyloxycarbonylamino)butyric acid
• CAS NO: 1607830-40-9
• Molecular Weight: 343.379
• Mol File: 1607830-40-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-3-(benzyloxy)-4-(benzyloxycarbonylamino)butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(benzyloxy)-4-(benzyloxycarbonylamino)butyric acid(1607830-40-9)
• EPA Substance Registry System: (S)-3-(benzyloxy)-4-(benzyloxycarbonylamino)butyric acid(1607830-40-9)

Safety Data

• Hazardous Substances Data: 1607830-40-9(Hazardous Substances Data)

Upstream product

• 838906-52-8 diethyl 3-(benzyloxy)pentanedioate 
• 100-39-0 benzyl bromide 
• 838906-36-8 meso-4-(benzyloxy)glutaric anhydride 

Downstream Products

• 7013-05-0 (S)-4-amino-3-hydroxybutanoic acid 

Relevant articles and documents

Synthesis of GABOB and GABOB-Based Chiral Units Possessing Distinct Protecting Groups

In addition to the varied biological activity of GABOB (4-amino-3-hydroxybutanoic acid), the structure of its protected derivatives makes them interesting chiral intermediates for the synthesis of more complex compounds. A stereoselective route to GABOB derivatives with three different protecting groups is presented, using anhydride desymmetrization as a chirality-inducing step. Selective removal of the protecting groups gave compounds with a free carboxylic acid or hydroxy group. Removal of all of the protecting groups allowed GABOB to be isolated in good yield and with excellent ee.