1609-93-4Relevant articles and documents
One-pot Synthesis of α,β-Butenolides from Methyl (Z)-3-Chloroacrylate
Barluenga, Jose,Fernandez, Jose R.,Yus, Miguel
, p. 183 - 184 (1986)
A one-pot synthesis of 4,4-disubstituted α,β-butenolides from methyl (Z)-3-chloroacrylate by successive addition of a Grignard reagent, lithiation, and carbonation is described.
FUSED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF
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Paragraph 0282, (2021/04/02)
The present disclosure relates to a class of fused pyrimidine compounds of Formula I, their stereoisomers, tautomers, pharmaceutically acceptable salts, polymorphs, solvates, and hydrates thereof. The present disclosure also relates to a process of preparation of these fused pyrimidine compounds, and to pharmaceutical compositions containing them.
A general access to optically pure epoxypolyynes: Asymmetric synthesis of antifeedant natural products
Grandjean,Pale,Chuche
, p. 5225 - 5236 (2007/10/02)
A general asymmetric approach toward cis-epoxypolyynes is described using optically pure (2R, 3S)-5-bromo-2,3-epoxy-4-pentyn-1-ol 1a as the key intermediate. From this intermediate, the synthesis of 2 epoxy polyyne natural products was carried out in 6 steps with a 42% overall yield.
