1609179-11-4Relevant articles and documents
Organocatalytic domino reactions: Synthesis of densely functionalized cyclohexene derivatives
Bi, Bo,Ding, Yuyang,Lou, Qinxin,Hu, Wenhui,Chan, Albert S.C.,Song, Hongrui,Zhao, Junling
supporting information, p. 3344 - 3347 (2014/06/09)
A highly enantioselective domino reaction of α,β-unsaturated aldehydes and 4-acetyl-5-oxohexanal catalyzed by a chiral secondary amine catalyst has been developed, providing an efficient synthetic approach for the synthesis of densely functionalized chiral cyclohexene derivatives with high yields (up to 96%) and enantioselectivities (up to 97% ee) under mild conditions.