1609191-04-9

Basic information

• Product Name: ⁽⁵⁾-tert-butyl 7-(((benzyloxy)carbonyl)amino)-7-(1H-imidazol-2-yl)heptanoate
• Synonyms: ⁽⁵⁾-tert-butyl 7-(((benzyloxy)carbonyl)amino)-7-(1H-imidazol-2-yl)heptanoate
• CAS NO: 1609191-04-9
• Molecular Weight: 401.506
• Mol File: 1609191-04-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ⁽⁵⁾-tert-butyl 7-(((benzyloxy)carbonyl)amino)-7-(1H-imidazol-2-yl)heptanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ⁽⁵⁾-tert-butyl 7-(((benzyloxy)carbonyl)amino)-7-(1H-imidazol-2-yl)heptanoate(1609191-04-9)
• EPA Substance Registry System: ⁽⁵⁾-tert-butyl 7-(((benzyloxy)carbonyl)amino)-7-(1H-imidazol-2-yl)heptanoate(1609191-04-9)

Safety Data

• Hazardous Substances Data: 1609191-04-9(Hazardous Substances Data)

Upstream product

• 1609191-02-7 (S)-tert-butyl 7-(((benzyloxy)carbonyl)amino)-8-(methoxy(methyl)amino)-8-oxooctanoate 
• 1609191-03-8 (S)-tert-butyl 7-(((benzyloxy)carbonyl)amino)-8-oxooctanoate 
• 4405-13-4 glyoxal trimer dihydrate 
• 49645-27-4 (S)-2-(((benzyloxy)carbonyl)amino)-8-(tert-butoxy)-8-oxooctanoic acid 

Downstream Products

• 1609191-06-1 (S)-tert-butyl 7-(((benzyloxy)carbonyl)amino)-7-(4,5-diiodo-1H-imidazol-2-yl)heptanoate 
• 1609191-08-3 (S)-benzyl (1-(5-iodo-1H-imidazol-2-yl)-7-(methylamino)-7-oxoheptyl)carbamate 
• 1609191-11-8 (S)-tert-butyl 7-(((benzyloxy)carbonyl)amino)-7-(5-(6-methoxynaphthalen-2-yl)-1H-imidazol-2-yl)heptanoate 
• 1609191-14-1 (S)-benzyl (1-(5-(6-methoxynaphthalen-2-yl)-1H-imidazol-2-yl)-7-(methylamino)-7-oxoheptyl)carbamate 
• 1609191-05-0 C₂₂H₃₀IN₃O₄ 

Relevant articles and documents

Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs

The identification of a new series of P. falciparum growth inhibitors is described. Starting from a series of known human class I HDAC inhibitors a SAR exploration based on growth inhibitory activity in parasite and human cells-based assays led to the identification of compounds with submicromolar inhibition of P. falciparum growth (EC50 50-fold). Inhibition of parasital HDACs as the mechanism of action of this new class of selective growth inhibitors is supported by hyperacetylation studies.