16097-62-4 Usage
Description
4-HYDROXY-2-(METHYLTHIO)-6-(TRIFLUOROMETHYL)PYRIMIDINE, also known as 2-(methylsulfanyl)-6-(trifluoromethyl)-4-pyrimidinol (CAS# 16097-62-4), is a white solid research chemical with potential applications in various scientific and industrial fields. Its unique chemical structure, featuring a hydroxyl group, a methylthio group, and a trifluoromethyl group, may contribute to its versatility and reactivity in chemical reactions and interactions.
Uses
Used in Research and Development:
4-HYDROXY-2-(METHYLTHIO)-6-(TRIFLUOROMETHYL)PYRIMIDINE is used as a research chemical for the development and study of new compounds and materials. Its unique properties and reactivity make it a valuable tool in the synthesis of novel molecules and the investigation of various chemical and biological processes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-HYDROXY-2-(METHYLTHIO)-6-(TRIFLUOROMETHYL)PYRIMIDINE may be used as a building block or intermediate in the synthesis of new drugs. Its chemical structure could potentially be modified to create new therapeutic agents with specific biological activities.
Used in Chemical Synthesis:
4-HYDROXY-2-(METHYLTHIO)-6-(TRIFLUOROMETHYL)PYRIMIDINE can be used as a starting material or reactant in the synthesis of various organic compounds. Its functional groups may allow for a range of reactions, such as substitution, addition, or condensation, leading to the formation of diverse chemical products.
Used in Material Science:
The unique properties of 4-HYDROXY-2-(METHYLTHIO)-6-(TRIFLUOROMETHYL)PYRIMIDINE may also find applications in material science, where it could be used to develop new materials with specific properties, such as improved stability, reactivity, or selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 16097-62-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,0,9 and 7 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 16097-62:
(7*1)+(6*6)+(5*0)+(4*9)+(3*7)+(2*6)+(1*2)=114
114 % 10 = 4
So 16097-62-4 is a valid CAS Registry Number.
16097-62-4Relevant articles and documents
2-methylsulfanyl-6-polyfluoroalkyl-pyrimidin-4-ones: Synthesis and nucleophilic substitution reactions
Khudina,Burgart, Ya. V.,Saloutin
, p. 856 - 863 (2014)
We have optimized the reaction conditions for the synthesis of 2-methylsulfanyl-6-polyfluoro-alkylpyrimidin-4-ones. In particular the yield of trifluoromethyl-substituted heterocycle was increased to 96%, and new polyfluoroalkyl-substituted analogs were prepared. The interaction of these heterocycles with morpholine or hydrazine was shown to result in nucleophilic substitution of the methylsulfanyl group, leading to 2-morpholino- and 2-hydrazino-6-polyfluoroalkylpyrimidin-4-ones. The reaction of 2-(2-phenylhydrazino)-6-trifluoromethylpyrimidin-4-one with paraform produced 5-oxo-2-phenyl-7-tri-fluoromethyl-5H-1,2,4-triazolo[4,3-a]pyrimidin-1-id-2-ium. The lactam structure of the synthesized heterocycles was established by X-ray structural analysis, as well as by IR and NMR spectroscopy.
2-methylsulfanyl-6-polyfluoroalkyl- pyrimidin-4-ones: Synthesis and nucleophilic substitution reactions
Khudina,Burgart,Saloutin
, p. 856 - 863 (2015/09/28)
We have optimized the reaction conditions for the synthesis of 2-methylsulfanyl-6-polyfluoro-alkylpyrimidin-4-ones. In particular the yield of trifluoromethyl-substituted heterocycle was increased to 96%, and new polyfluoroalkyl-substituted analogs were prepared. The interaction of these heterocycles with morpholine or hydrazine was shown to result in nucleophilic substitution of the methylsulfanyl group, leading to 2-morpholino- and 2-hydrazino-6-polyfluoroalkylpyrimidin-4-ones. The reaction of 2-(2-phenylhydrazino)-6-trifluoromethylpyrimidin-4-one with paraform produced 5-oxo-2-phenyl-7-tri-fluoromethyl-5H-1,2,4-triazolo[4,3-a]pyrimidin-1-id-2-ium. The lactam structure of the synthesized heterocycles was established by X-ray structural analysis, as well as by IR and NMR spectroscopy.
