1610362-71-4

Basic information

• Product Name: 3-bromo-1-(4-methoxybenzyl)-7-nitro-1H-indazole
• Synonyms: 3-bromo-1-(4-methoxybenzyl)-7-nitro-1H-indazole
• CAS NO: 1610362-71-4
• Molecular Weight: 362.183
• Mol File: 1610362-71-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-bromo-1-(4-methoxybenzyl)-7-nitro-1H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-1-(4-methoxybenzyl)-7-nitro-1H-indazole(1610362-71-4)
• EPA Substance Registry System: 3-bromo-1-(4-methoxybenzyl)-7-nitro-1H-indazole(1610362-71-4)

Safety Data

• Hazardous Substances Data: 1610362-71-4(Hazardous Substances Data)

Upstream product

• 74209-34-0 3-bromo-7-nitro-1H-indazole 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 1610362-73-6 1-(4-methoxybenzyl)-3-phenyl-1H-indazol-7-amine 
• 1610362-74-7 phenyl (1-(4-methoxybenzyl)-3-phenyl-1H-indazol-7-yl)carbamate 
• 1610362-72-5 1-(4-methoxybenzyl)-7-nitro-3-phenyl-1H-indazole 

Relevant articles and documents

PYRROLIDINYL UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS AS TRKA KINASE INHIBITORS

Compounds of Formula I: or stereoisomers, tautomers, or pharmaceutically acceptable salts, or solvates or prodrugs thereof, where R1, R2, Ra, Rb, Rc, Rd, X, Ring B, and Ring C are as defined herein, and wherein Ring B moiety and the NH-C(=X)-NH moiety are in the trans configuration, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.