1610522-93-4

Basic information

• Product Name: 7,8-bis(benzyloxy)-4-hydroxy-2H-chromen-2-one
• Synonyms: 7,8-bis(benzyloxy)-4-hydroxy-2H-chromen-2-one
• CAS NO: 1610522-93-4
• Molecular Weight: 374.393
• Mol File: 1610522-93-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 7,8-bis(benzyloxy)-4-hydroxy-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7,8-bis(benzyloxy)-4-hydroxy-2H-chromen-2-one(1610522-93-4)
• EPA Substance Registry System: 7,8-bis(benzyloxy)-4-hydroxy-2H-chromen-2-one(1610522-93-4)

Safety Data

• Hazardous Substances Data: 1610522-93-4(Hazardous Substances Data)

Upstream product

• 2652-27-9 1-(3,4-bis(benzyloxy)-2-hydroxyphenyl)ethanone 
• 105-58-8 Diethyl carbonate 
• 528-21-2 2',3',4'-trihydroxyacetophenone 
• 100-39-0 benzyl bromide 
• 50439-63-9 1-(2,3,4-tris(benzyloxy)phenyl)ethanone 
• 1643318-41-5 ethyl 3-(3,4-bis(benzyloxy)phenyl)-3-oxopropanoate 

Downstream Products

• 1642785-09-8 7,8-bis(benzyloxy)-2-oxo-2H-chromen-4-yl trifluoromethanesulfonate 
• 1642784-52-8 7,8-bis(benzyloxy)-4-(3-(benzyloxy)-4-methoxyphenyl)-2H-chromen-2-one 
• 1267949-42-7 7,8-dihydroxy-4-(3-hydroxy-4-methoxyphenyl)-3,4-dihydrocoumarin 
• 842-01-3 7,8-dihydroxy-4-phenyl-2H-chromen-2-one 
• 185033-52-7 7,8-dihydroxy-4-(3',4'-dimethoxyphenyl)-2H-1-chromen-2-one 
• 370582-94-8 7,8-dihydroxy-4-(4-methoxyphenyl)-2H-chromen-2-one 

Relevant articles and documents

Synthesis and anticancer activity of 7,8-dihydroxy-4-arylcoumarins

A series of 7,8-dihydroxy-4-arylcoumarins, the derivatives related to DW532 that was an anti-tumor agent targeting both kinase and tubulin, was prepared by Suzuki coupling reaction. Among them, compounds 6a, 6b, and 6c were found to exhibit anti-prolifera

Design and synthesis of 3,3′-biscoumarin-based c-Met inhibitors

A library of biscoumarin-based c-Met inhibitors was synthesized, based on optimization of 3,3′-biscoumarin hit 3, which was identified as a non-ATP competitive inhibitor of c-Met from a diverse library of coumarin derivatives. Among these compounds, 38 and 40 not only showed potent enzyme activities with IC50 values of 107 nM and 30 nM, respectively, but also inhibited c-Met phosphorylation in BaF3/TPR-Met and EBC-1 cells. This journal is the Partner Organisations 2014.