16111-50-5Relevant articles and documents
A family of hydrazone-based nucleosides for use in metal-mediated base pairs
Radunsky, Christian,Megger, Dominik A.,Hepp, Alexander,Koesters, Jutta,Freisinger, Eva,Mueller, Jens
, p. 1621 - 1627 (2013)
A new family of hydrazone-based nucleosides for use in metal-mediated base pairs was devised. The artificial nucleobases are derivatives of the papy ligand (papy = pyridinecarboxaldehyde-2′-pyridylhydrazone). By replacing the pendant pyridine moiety in papy by furan and thiophene, respectively, tridentate nucleosides with N, N, N-, N, N, O- and N, N, S-donor sites were obtained. As only a few transition metal complexes with pendant furan ligands have been reported, a model nucleobase for the N, N, O-donor nucleoside was synthesized. The molecular structures of its Cu2+, Ni2+, and Co 2+ complexes are reported. In all complexes, only weak M-O(furan) bonding is observed. The Co2+ complex displays a pentagonal bipyramidal coordination arrangement. In general, the structures of the metal complexes suggest that the respective nucleosides can be applied in metal-mediated base pairs. Copyright
Metal transition complexes of tridentate Schiff base ligands derived from 2-hydrazinopyridine: synthesis, spectroscopic characterization and X-ray structures
Diop, Amar,Sarr, Mamou,Diop, Mayoro,Thiam, Ibrahima Elhadj,Barry, Aliou Hamady,Coles, Simon,Orton, James,Gaye, Mohamed
, p. 415 - 423 (2019)
Mononuclear complexes of 1-(pyridin-2-ylmethylidene)-2-(pyridin-2-yl)hydrazine (HL1) and 1-(pyridin-2-yl)-2-(1-(pyridin-2-yl)ethylidene)hydrazine (HL2), [Mn(HL1)(Cl2)(H2O)] (1), [Zn(HL1)(CH3COO)2]·(H2O)3 (2), [Mn(HL2)2]·(ClO4)2 (3) and [Cu(HL2)(NO3)2(H2O)] (4) were synthesized and characterized by physicochemical and spectroscopic methods and X-ray structure determination. The mononuclear compounds 1, 2 and 4 contain one ligand molecule per metal atom while the manganese (II) atom in compound 3 is coordinated to two ligand molecules. Both ligands coordinated to the transition metal center in?a tridentate fashion through two Npyridyl atoms and one Nimino atom. The chloride and acetate anions coordinate in monodentate manner, respectively, in complex 1 and in complex 2. In complex 3, the perchlorate groups remain uncoordinated. In complex 4, the nitrate anions act in unidentate fashion. The molar conductance value indicates that the complexes obtained from HL1 are non-electrolytes while those obtained from HL2 are 2:1 electrolytes in DMF solutions. The X-ray structures reveal octahedral geometry for complexes 1, 3, 4 and trigonal bipyramidal environment for 2.
Phosphine-Free NNN-Manganese Complex Catalyzed α-Alkylation of Ketones with Primary Alcohols and Friedl?nder Quinoline Synthesis
Barman, Milan K.,Jana, Akash,Maji, Biplab
supporting information, p. 3233 - 3238 (2018/07/31)
Herein, we report a very simple and inexpensive catalytic system based on Earth's abundant transition metal manganese and on a bench-stable phosphine-free NNN-pincer ligand for an atom-efficient α-alkylations of ketones with primary alcohols via hydrogen-autotransfer C?C bond formation protocol. The precatalyst could be generated in situ and could be activated by using catalytic amount of base under milder conditions. A range of ketones were efficiently diversified with a broad range of primary alcohols in good to excellent isolated yields. Remarkably, this catalyst could also be employed for the synthesis of quinoline derivatives using 2-aminobenzyl alcohol as an alkylating agent. The later reaction is highly benign producing only hydrogen and water as byproducts. (Figure presented.).
