1611477-31-6

Basic information

• Product Name: C₁₂H₁₄ClNO₂
• Synonyms: C₁₂H₁₄ClNO₂
• CAS NO: 1611477-31-6
• Molecular Weight: 239.702
• Mol File: 1611477-31-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₄ClNO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₄ClNO₂(1611477-31-6)
• EPA Substance Registry System: C₁₂H₁₄ClNO₂(1611477-31-6)

Safety Data

• Hazardous Substances Data: 1611477-31-6(Hazardous Substances Data)

Upstream product

• 94-09-7 p-aminoethylbenzoate 
• 132371-06-3 ethyl 4-propionamidobenzoate 

Downstream Products

• 100390-21-4 C₁₂H₁₅NO₂ 

Relevant articles and documents

Semi-catalytic reduction of secondary amides to imines and aldehydes

Secondary amides can be reduced by silane HSiMe2Ph into imines and aldehydes by a two-stage process involving prior conversion of amides into iminoyl chlorides followed by catalytic reduction mediated by the ruthenium complex [Cp(i-Pr3P)Ru(NCCH3)2]PF6 (1). Alkyl and aryl amides bearing halogen, ketone, and ester groups were converted with moderate to good yields under mild reaction conditions to the corresponding imines and aldehydes. This procedure does not work for substrates bearing the nitro-group and fails for heteroaromatic amides. In the case of cyano substituted amides, the cyano group is reduced to imine.