1612-41-5Relevant articles and documents
Copper-Mediated Decarboxylative Sulfonylation of Arylacetic Acids with Sodium Sulfinates
Wu, Yinrong,Chen, Jiewen,Li, Lu,Wen, Kangmei,Yao, Xingang,Pang, Jianxin,Wu, Ting,Tang, Xiaodong
supporting information, p. 7164 - 7168 (2020/10/02)
Herein, we present a copper-mediated decarboxylative sulfonylation of arylacetic acids with sodium sulfinates that provides viable access to sulfone compounds. This protocol features readily available feedstocks, simple operations, high regioselectivities, and moderate to good yields. The newly obtained products could be converted to other useful compounds. Importantly, the products and their derivatives exhibited potent antitumor activities in vitro, which were tested by MTT assay.
