1613027-86-3

Basic information

• Product Name: tert-butyl [2-(pyrimidin-2-yl)phenyl]carbamate
• Synonyms: tert-butyl [2-(pyrimidin-2-yl)phenyl]carbamate
• CAS NO: 1613027-86-3
• Molecular Weight: 271.319
• Mol File: 1613027-86-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-butyl [2-(pyrimidin-2-yl)phenyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl [2-(pyrimidin-2-yl)phenyl]carbamate(1613027-86-3)
• EPA Substance Registry System: tert-butyl [2-(pyrimidin-2-yl)phenyl]carbamate(1613027-86-3)

Safety Data

• Hazardous Substances Data: 1613027-86-3(Hazardous Substances Data)

Upstream product

• 98-80-6 phenylboronic acid 
• 7431-45-0 2-phenylpyrimidine 
• 17508-16-6 tert-butyl (2,4-dinitrophenoxy)carbamate 
• 99768-83-9 (acetyloxy)carbamic acid 1,1-dimethyl ethyl ester 
• 36016-38-3 tert-Butyl N-hydroxycarbamate 
• 1613027-54-5 methyl 4-[{(tert-butoxycarbonyl)amino}oxycarbonyl]benzoate 

Relevant articles and documents

2-catalyzed directed N -Boc amidation of arenes "on water"

Rhodium(III) catalysis "on water" is effective for directed C-H amidation of arenes. The catalytic process is promoted by OH groups present on the hydrophobic water surface and is inefficient in all (most) common organic solvents investigated so far. In the presence of easily prepared tert-butyl 2,4-dinitrophenoxycarbamate, a new and stable nitrene source, the "on water" reaction can efficiently provide the desired N-Boc-aminated products with good functional group tolerance.

N -substituted hydroxylamines as synthetically versatile amino sources in the iridium-catalyzed mild C-H amidation reaction

N-Substituted hydroxylamines such as aroyloxy- or acyloxycarbamates were successfully employed as synthetically versatile amino precursors in the iridium-catalyzed direct C-H amidation of arenes. The reaction proceeds smoothly at room temperature over a broad range of substrates with high functional group tolerance to afford N-substituted arylamine products.