1613234-40-4

Basic information

• Product Name: 2-amino-4-(4-chloro-3-nitrophenyl)-6-hydroxymethyl-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile
• Synonyms: 2-amino-4-(4-chloro-3-nitrophenyl)-6-hydroxymethyl-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile
• CAS NO: 1613234-40-4
• Molecular Weight: 375.725
• Mol File: 1613234-40-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-amino-4-(4-chloro-3-nitrophenyl)-6-hydroxymethyl-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-(4-chloro-3-nitrophenyl)-6-hydroxymethyl-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile(1613234-40-4)
• EPA Substance Registry System: 2-amino-4-(4-chloro-3-nitrophenyl)-6-hydroxymethyl-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile(1613234-40-4)

Safety Data

• Hazardous Substances Data: 1613234-40-4(Hazardous Substances Data)

Upstream product

• 501-30-4 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 
• 109-77-3 malononitrile 
• 16588-34-4 4-chloro-3-nitro-benzaldehyde 

Relevant articles and documents

SiO2-OSO3H nanoparticles: An efficient, versatile and new reagent for the one-pot synthesis of 2-amino-8-oxo-4,8-dihydropyrano[3,2-b] pyran-3-carbonitrile derivatives in water, a green protocol

In a one-pot three-component reaction, an aromatic or aliphatic aldehyde, malononitrile and 5-hydroxy-2-hydroxymethyl-4H-pyran-4-one were condensed for the synthesis of 2-amino-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile derivatives in the presence of nano-silica sulfuric acid (SiO 2-OSO3H nanoparticles) in improved yields. The catalyst is recoverable by simple filtration and can be used in the subsequent reactions.