16134-40-0

Basic information

• Product Name: cholesterol trimethylsilyl ether
• CAS NO: 16134-40-0
• Molecular Weight: 458.844
• Mol File: 16134-40-0.mol
• Article Data: 38

Chemical Properties

• CAS DataBase Reference: cholesterol trimethylsilyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: cholesterol trimethylsilyl ether(16134-40-0)
• EPA Substance Registry System: cholesterol trimethylsilyl ether(16134-40-0)

Safety Data

• Hazardous Substances Data: 16134-40-0(Hazardous Substances Data)

Upstream product

• 57-88-5 cholesterol 
• 4039-32-1 lithium hexamethyldisilazane 
• 54380-53-9 cyclohexa-2,5-dien-1-yl(trimethyl)silane 
• 21149-38-2 2,2,2-trifluoro-N,N-bis(trimethylsilyl)-acetamide 
• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 
• 75-77-4 chloro-trimethyl-silane 
• 601-54-7 Cholest-5-en-3-one 
• 53296-64-3 N-methyl-N-trimethylsilyl-heptafluoro-butyramide 
• 25561-30-2 N,O-Bis(trimethylsilyl)trifluoroacetamide 
• 18297-63-7 N,N'-bis(trimethylsilyl)urea 
• 1066-40-6 Trimethylsilanol 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 57-88-5 cholesterol 

Downstream Products

• 601-54-7 Cholest-5-en-3-one 
• 604-35-3 Cholesteryl acetate 
• 601-57-0 Cholest-4-en-3-one 
• 95898-07-0 3β-cholesteryl 2,3,4-tri-O-benzyl-β-D-xylopyranoside 
• 95898-07-0 3β-cholesteryl 2,3,4-tri-O-benzyl-α-D-xylopyranoside 
• 41736-89-4 3-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)cholesterol 
• 70753-59-2 O-[2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl]cholesterol 

Relevant articles and documents

A Convenient Method for Protection and Deprotection of Alcohols and Phenols as Alkylsilyl Ethers Catalyzed by Iodine under Microwave Irradiation

Irradiation of alcohols or phenols with tert-butyldimethylsilyl chloride (TBDMSCl) or trimethylsilyl chloride (TMSCl) in presence of catalytic amount (20 mol%) of iodine in a microwave oven for 2 min gives the corresponding silyl ethers in excellent yield. Iodine in methanol deprotects the silyl ether into its parent alcohol or phenol under similar reaction conditions.

SATURATED AND UNSATURATED STEROLS OF NITROGEN-FIXING BLUE-GREEN ALGAE (CYANOBACTERIA)

Five species of filamentous nitrogen-fixing blue-green algae (Cyanobacteria), (Anabaena cylindrica, Anabaena solitaria, Anabaena viguieri, Nostoc carneum, Nodularia harveyana) were grown in a freshwater medium containing 10percent seawater(DS medium).The sterols were analysed by means of a newly developed procedure involving precipitation with digitonine, GC and GC/MS but not TLC and CC.All species were found to synthesize a great variety of sterols (11-15 compounds).The digitonin precipitable sterols made up ca 0.005-0.03percent of the dried algal biomass.Remarkably, each species produced the saturated sterols, 5α-cholestan-3β-ol, 24-methyl-5α-cholestan-3β-ol and 24-ethyl-5α-cholestan-3β-ol.The latter was the main sterol in all organisms.Furthermore, the investigated microalgae were found to synthesize known C27, C28 and C29 sterols.Key Word Index-blue-green algae; nitrogen-fixing blue-green algae; sterols; cyanobacteria.

Selective silylation of alcohols, phenols and oximes using N-chlorosaccharin as an efficient catalyst under mild and solvent-free conditions

Efficient silylation of OH group in alcohols, phenols and oximes is described using a catalytic amount of N-chlorosaccharin and hexamethyldisilazane (HMDS) under mild and solvent-free conditions. This silylation reaction can be carried out with excellent and interesting various selectivities.

Highly atom economical uncatalysed and I2-catalysed silylation of phenols, alcohols and carbohydrates, using HMDS under solvent-free reaction conditions (SFRC)

An uncatalysed silylation of phenols, regardless on the aggregate state and nature of the substituents with 0.55 equiv of HMDS under solvent-free reaction conditions (SFRC) at room temperature is reported. Sterically hindered phenols, carbohydrates and most of the alcohols additionally required a catalytic amount (up to 2 mol %) of iodine. The reaction protocol is very simple; obtaining a pure product, particularly of uncatalysed reactions, was frequently a completely solvent-free process.