161344-85-0

Basic information

• Product Name: 2-BUTYL-[1,3,2]DIOXABOROLANE-4,5-DICARBOXYLIC ACID BIS-DIMETHYLAMIDE
• Synonyms: (4R,5R)-2-BUTYL-N,N,N',N'-TETRAMETHYL-1,3,2-DIOXABOROLANE-4,5-DICARBOXAMIDE;2-BUTYL-N,N,N',N'-TETRA-METHYL-1,3,2-DIOXABOROLANE-4,5, DICARBOXAMIDE;2-BUTYL-N,N,N',N'-TETRAMETHYL-1,3,2-DIOXABOROLANE-(4R,5R)-DICARBOXAMIDE;2-BUTYL-[1,3,2]DIOXABOROLANE-4,5-DICARBOXYLIC ACID BIS-DIMETHYLAMIDE;2-BUTYL-1,3,2-DIOXABOROLANE-4R,5R-DICARBOXYLIC ACID BIS(DIMETHYLAMIDE);Butylboronic acid N,N,N',N'-tetramethyl-L-tartaric acid diamide ester;2-Butyl-1,3,2-dioxaborolane-4R,5R-dicarboxylic;(4R,5R)-2-Butyl-1,3,2-dioxaborolane-4,5-dicarboxylic acid bis(dimethylamide)
• CAS NO: 161344-85-0
• Molecular Formula: C12H23BN2O4
• Molecular Weight: 270.13
• Product Categories: Heterocyclic Compounds
• Mol File: 161344-85-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 178-179 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.072 g/mL at 25 °C(lit.)
• Vapor Pressure: 8.04E-07mmHg at 25°C
• Refractive Index: n20/D 1.478(lit.)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: -0.81±0.40(Predicted)
• CAS DataBase Reference: 2-BUTYL-[1,3,2]DIOXABOROLANE-4,5-DICARBOXYLIC ACID BIS-DIMETHYLAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BUTYL-[1,3,2]DIOXABOROLANE-4,5-DICARBOXYLIC ACID BIS-DIMETHYLAMIDE(161344-85-0)
• EPA Substance Registry System: 2-BUTYL-[1,3,2]DIOXABOROLANE-4,5-DICARBOXYLIC ACID BIS-DIMETHYLAMIDE(161344-85-0)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 23-24/25
• WGK Germany: 3
• Hazardous Substances Data: 161344-85-0(Hazardous Substances Data)

Usage

Description

2-BUTYL-[1,3,2]DIOXABOROLANE-4,5-DICARBOXYLIC ACID BIS-DIMETHYLAMIDE, also known as Butylboronic acid N,N,N′,N′-tetramethyl-L-tartaric acid diamide ester, is a chemical compound with a complex structure that features a dioxaborolane ring and two dimethylamide groups. It is known for its potential applications in the synthesis of various natural products and pharmaceutical compounds.

Uses

Used in Pharmaceutical Synthesis:
2-BUTYL-[1,3,2]DIOXABOROLANE-4,5-DICARBOXYLIC ACID BIS-DIMETHYLAMIDE is used as a cyclopropanation ligand for the total synthesis of natural products and pharmaceutical compounds. Its unique structure allows it to participate in key reactions, facilitating the formation of complex molecular architectures.
Used in Marine Natural Products Synthesis:
In the field of marine natural products, 2-BUTYL-[1,3,2]DIOXABOROLANE-4,5-DICARBOXYLIC ACID BIS-DIMETHYLAMIDE is used as a cyclopropanation ligand for the synthesis of (+)-Frondosin, a natural product derived from marine sponges. 2-BUTYL-[1,3,2]DIOXABOROLANE-4,5-DICARBOXYLIC ACID BIS-DIMETHYLAMIDE has shown potential biological activities, making it an important target for pharmaceutical research.
Used in Cyanobacterium Natural Products Synthesis:
2-BUTYL-[1,3,2]DIOXABOROLANE-4,5-DICARBOXYLIC ACID BIS-DIMETHYLAMIDE is also used in the synthesis of coibacins A and B, which are natural products derived from marine cyanobacteria. These compounds have demonstrated various biological properties, making them valuable for the development of new drugs and therapeutic agents.

InChI:InChI=1/C12H23BN2O4/c1-6-7-8-13-18-9(11(16)14(2)3)10(19-13)12(17)15(4)5/h9-10H,6-8H2,1-5H3/t9-,10-/m1/s1