161419-78-9

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 6-amino-1-butyl-3-(phenylmethyl)-
• CAS NO: 161419-78-9
• Molecular Formula: C15H19N3O2
• Molecular Weight: 273.335
• Mol File: 161419-78-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 6-amino-1-butyl-3-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 6-amino-1-butyl-3-(phenylmethyl)-(161419-78-9)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 6-amino-1-butyl-3-(phenylmethyl)-(161419-78-9)

Safety Data

• Hazardous Substances Data: 161419-78-9(Hazardous Substances Data)

Upstream product

• 53681-49-5 6-amino-1-n-butyl-1,3-dihydropyrimidine-2,4-dione 
• 592-31-4 1-butyl-urea 
• 100-39-0 benzyl bromide 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 111-36-4 n-butyl isocyanide 
• 14117-22-7 N-benzyl-N′-butylurea 

Downstream Products

• 628279-18-5 2-(4-acetylamino-phenyl)-N-(6-amino-3-benzyl-1-butyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-acetamide 
• 628279-23-2 3-benzyl-5,6-diamino-1H-pyrimidine-2,4-dione 

Relevant articles and documents

Amide substituted xanthine derivatives

The present invention is a 1,3,8 substituted xanthine derivative of formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2 and R3 are as defined in the specification. Compounds of formula I and pharmaceutically acceptable salts or prodrugs thereof show activity as modulators of gluconeogenesis.

Modified 3-alkyl-1,8-dibenzylxanthines as GTP-competitive inhibitors of phosphoenolpyruvate carboxykinase

The first non-substrate like inhibitors of human cytosolic phosphoenolpyruvate carboxykinase (PEPCK) competitive with GTP are reported. An effort to discover orally active compounds that improve glucose homeostasis in Type 2 diabetics by reversibly inhibi