1615653-04-7

Basic information

• Product Name: N-benzyl-N-(2-ethynylphenyl)-2-oxoheptanamide
• Synonyms: N-benzyl-N-(2-ethynylphenyl)-2-oxoheptanamide
• CAS NO: 1615653-04-7
• Molecular Weight: 333.43
• Mol File: 1615653-04-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl-N-(2-ethynylphenyl)-2-oxoheptanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-N-(2-ethynylphenyl)-2-oxoheptanamide(1615653-04-7)
• EPA Substance Registry System: N-benzyl-N-(2-ethynylphenyl)-2-oxoheptanamide(1615653-04-7)

Safety Data

• Hazardous Substances Data: 1615653-04-7(Hazardous Substances Data)

Upstream product

• 76464-99-8 N-benzyl-2-iodoaniline 
• 13088-48-7 2-oxoheptanoic acid 
• 324738-51-4 2′-N-benzylaminophenylacetylene 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 1615653-16-1 1-benzyl-3-diethoxyphosphoryloxy-4-methylene-3-(pentan-1-yl)-3,4-dihydro-2-quinolone 
• 1615653-30-9 C₂₆H₃₄NO₅P 

Relevant articles and documents

Intramolecular cyclization of alkynyl α-ketoanilide utilizing [1,2]-phospha-brook rearrangement catalyzed by phosphazene base

A novel catalytic cyclization reaction of alkynyl α-ketoanilide was developed by utilizing the [1,2]-phospha-Brook rearrangement. This reaction involves the generation of an amide enolate via the umpolung process, that is the addition of dialkyl phosphite to a keto moiety followed by the [1,2]-phospha-Brook rearrangement, and the subsequent intramolecular addition of the enolate to an alkyne to afford 3,4-dihydro-2-quinolone derivatives. Under high-temperature reaction conditions, further rearrangement of the allylic phosphate moiety occurs to provide 2-quinolone derivatives.