1616489-30-5

Basic information

• Product Name: C₈H⁽²⁾H₉
• CAS NO: 1616489-30-5
• Molecular Weight: 115.096
• Mol File: 1616489-30-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₈H⁽²⁾H₉(CAS DataBase Reference)
• NIST Chemistry Reference: C₈H⁽²⁾H₉(1616489-30-5)
• EPA Substance Registry System: C₈H⁽²⁾H₉(1616489-30-5)

Safety Data

• Hazardous Substances Data: 1616489-30-5(Hazardous Substances Data)

Upstream product

• 56004-61-6 o-xylene-d10 

Relevant articles and documents

Pd-catalyzed aerobic oxidative coupling of arenes: Evidence for transmetalation between two Pd(II)-aryl intermediates

Pd-catalyzed aerobic oxidative coupling of arenes provides efficient access to biaryl compounds. The biaryl product forms via C-H activation of two arenes to afford a PdIIArAr' intermediate, which then undergoes C-C reductive elimination. The key PdIIArAr' intermediate could form via a monometallic pathway involving sequential C-H activation at a single PdII center, or via a bimetallic pathway involving parallel C-H activation at separate PdII centers, followed by a transmetalation step between two PdII-aryl intermediates. Here, we investigate the oxidative coupling of o-xylene catalyzed by a PdX 2/2-fluoropyridine catalyst (X = trifluoroacetate, acetate). Kinetic studies, H/D exchange experiments, and kinetic isotope effects provide clear support for a bimetallic/transmetalation mechanism.