1616761-72-8

Basic information

• Product Name: benzyl [3-(nitromethyl)oxetan-3-yl]-L-leucinate
• CAS NO: 1616761-72-8
• Molecular Weight: 336.388
• Mol File: 1616761-72-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl [3-(nitromethyl)oxetan-3-yl]-L-leucinate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl [3-(nitromethyl)oxetan-3-yl]-L-leucinate(1616761-72-8)
• EPA Substance Registry System: benzyl [3-(nitromethyl)oxetan-3-yl]-L-leucinate(1616761-72-8)

Safety Data

• Hazardous Substances Data: 1616761-72-8(Hazardous Substances Data)

Upstream product

• 922500-95-6 3-(nitromethylene)oxetane 
• 1738-77-8 L-leucine benzyl ester p-toluenesulfonate 

Relevant articles and documents

Synthesis and structure of oxetane containing tripeptide motifs

A new class of peptidomimetic is reported in which one of the amide CO bonds of the peptide backbone is replaced by an oxetane ring. They are synthesised by conjugate addition of various α-amino esters to a 3-(nitromethylene)oxetane, reduction of the nitro group and further coupling with N-Z protected amino acids to grow the peptide chain. Structural insights are provided by X-ray diffraction and molecular dynamics simulations.