16168-92-6 Usage
Derivative of pyrrole
This compound is derived from pyrrole, which is a five-membered aromatic ring with four carbon atoms and one nitrogen atom.
Structure
The structure of 1H-Pyrrole-2-carboxaldehyde, 4-acetyl(9CI) contains a pyrrole ring with a carboxaldehyde and an acetyl group attached.
Use in organic synthesis
This compound is commonly used as a reagent in organic synthesis for the manufacture of various pharmaceuticals, agrochemicals, and fine chemicals.
Biological and pharmacological activities
1H-Pyrrole-2-carboxaldehyde, 4-acetyl(9CI) has been studied for its potential biological and pharmacological activities, including anti-inflammatory and anti-cancer properties.
Building block for heterocyclic compounds
This compound is also used as a building block for the synthesis of heterocyclic compounds, which are organic compounds containing a ring of atoms with at least one non-carbon atom.
Flavor and fragrance ingredient
1H-Pyrrole-2-carboxaldehyde, 4-acetyl(9CI) is also used as a flavor and fragrance ingredient in the food and cosmetic industries.
Check Digit Verification of cas no
The CAS Registry Mumber 16168-92-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,1,6 and 8 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 16168-92:
(7*1)+(6*6)+(5*1)+(4*6)+(3*8)+(2*9)+(1*2)=116
116 % 10 = 6
So 16168-92-6 is a valid CAS Registry Number.
16168-92-6Relevant articles and documents
The synthesis, characterization and optical properties of novel 2-Acyl 6-Arylindolizines
Ge, Yan Qing,Gong, Xue Yong,Song, Guang Jie,Cao, Xiao Qun,Wang, Jian Wu
, p. 7 - 13 (2014/08/05)
A series of novel 2-Acyl-6-Aryl substituted indolizine derivatives was synthesized by a novel tandem reaction between 4-Acyl-pyrrole-2-carbaldehyde derivatives and ethyl 4-bromo-3-Arylbut-2-enoate under mild conditions. The compounds were characterized using IR, 1H NMR 13C NMR and HRMS. The crystal structure of 7a was determined using single crystal X-ray crystallography. The absorption results showed that compounds 7a-e presented their absorption maxima at ca. 270 nm, while compounds 7f and 7g with a larger conjugation system exhibited red-shifted absorption character (ca. 280 nm). Fluorescence spectra revealed that these compounds exhibited blue fluorescence (434-456 nm) in dilute solutions and showed quantum yields of fluorescence between 0.02 and 0.39 in dichloromethane.
