16180-37-3

Basic information

• Product Name: (5R,6R,7R,9R,13S,14R,20S)-4,5-Epoxy-3,6-dimethoxy-α,17-dimethyl-α-phenyl-6,14-ethenomorphinan-7-methanol
• Synonyms: (5R,6R,7R,9R,13S,14R,20S)-4,5-Epoxy-3,6-dimethoxy-α,17-dimethyl-α-phenyl-6,14-ethenomorphinan-7-methanol
• CAS NO: 16180-37-3
• Molecular Weight: 459.585
• Mol File: 16180-37-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (5R,6R,7R,9R,13S,14R,20S)-4,5-Epoxy-3,6-dimethoxy-α,17-dimethyl-α-phenyl-6,14-ethenomorphinan-7-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (5R,6R,7R,9R,13S,14R,20S)-4,5-Epoxy-3,6-dimethoxy-α,17-dimethyl-α-phenyl-6,14-ethenomorphinan-7-methanol(16180-37-3)
• EPA Substance Registry System: (5R,6R,7R,9R,13S,14R,20S)-4,5-Epoxy-3,6-dimethoxy-α,17-dimethyl-α-phenyl-6,14-ethenomorphinan-7-methanol(16180-37-3)

Safety Data

• Hazardous Substances Data: 16180-37-3(Hazardous Substances Data)

Upstream product

• 917-64-6 methyl magnesium iodide 
• 464-66-4 nepenthone 
• 74-88-4 methyl iodide 
• 15358-22-2 thevinone 

Downstream Products

• 18063-43-9 4,5α-epoxy-3-methoxy-17-methyl-14-((Ξ)-3-phenyl-butyl)-morphinan-6α-ol 
• 18063-42-8 4,5α-epoxy-3-methoxy-17-methyl-14-((Ξ)-3-phenyl-but-2-enyl)-morphinan-6α-ol 
• 18063-41-7 4,5α-epoxy-3-methoxy-17-methyl-14-((Ξ)-3-phenyl-but-2-enyl)-morphinan-6β-ol 
• 18463-98-4 4,5α-epoxy-3-methoxy-17-methyl-14-((Ξ)-3-phenyl-but-2-enyl)-morphin-7-en-6α-ol 
• 16540-92-4 4,5α-epoxy-3-methoxy-17-methyl-14-((Ξ)-3-phenyl-but-2-enyl)-morphinan-6-one 
• 188341-25-5 C₂₇H₂₉NO₄ 
• 188341-17-5 C₂₉H₃₀N₂O₄ 
• 16196-72-8 6,7,8,14-tetrahydro-7α-(α-hydroxy-α-methylbenzyl)-6,14-endo-ethanothebaine 
• 16540-88-8 4,5α-epoxy-3-methoxy-17-methyl-14-((Ξ)-3-phenyl-but-2-enyl)-morphin-7-en-6-one 
• 16609-85-1 4,5α-epoxy-19anti-((S)-1-hydroxy-1-phenyl-ethyl)-6-methoxy-17-methyl-8β,14-ethano-morphin-7-en-3-ol 
• 6387-61-7 4,5α-epoxy-3-methoxy-17-methyl-5'-phenyl-(8α)-3',6'-dihydro-8H-benzo[8,14]morphinan-6-one 
• 6746-90-3 4,5α-epoxy-3-methoxy-17-methyl-5'-phenyl-(8α)-3',4'-dihydro-8H-benzo[8,14]morphinan-6-one 
• 6387-62-8 4,5α-epoxy-3-methoxy-17-methyl-5'-phenyl-(8α)-3',6'-dihydro-8H-benzo[8,14]morphinan-6ξ-ol 

Relevant articles and documents

Nuclear magnetic resonance studies in the 6,14-endo-ethenotetrahydrothebaine series.

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Synthesis of new nepenthone derivatives

Hydrogenation of nepenthone (3a) leads to a mixture of dihydronepenthone (3c) and the secondary alcohol (20S)-4b. The enantiomeric secondary alcohol (20R)-4b is prepared from the 7α-formyl-6,14-ethenomorphinan derivative 3b by reaction with phenylmagnesiu