16180-99-7

Basic information

• Product Name: Benzamide, N-[2-(benzoyloxy)ethyl]-
• Synonyms: 1-benzoylamino-2-benzoyloxy-ethane;N-benzoylmonoethanolamine benzoate;2-(phenylformamido)ethyl benzoate;N,O-dibenzoyl-2-aminoethanol;1-Benzoylamino-2-benzoyloxy-aethan;2-(benzoylamino)ethyl benzoate
• CAS NO: 16180-99-7
• Molecular Formula: C16H15NO3
• Molecular Weight: 269.3
• Mol File: 16180-99-7.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzamide, N-[2-(benzoyloxy)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-[2-(benzoyloxy)ethyl]-(16180-99-7)
• EPA Substance Registry System: Benzamide, N-[2-(benzoyloxy)ethyl]-(16180-99-7)

Safety Data

• Hazardous Substances Data: 16180-99-7(Hazardous Substances Data)

Upstream product

• 497-25-6 dimethylenecyclourethane 
• 65-85-0 benzoic acid 
• 7127-19-7 2-phenyl-1,3-oxazoline 
• 98-88-4 benzoyl chloride 
• 27110-61-8 N-(2-Bromo-ethyl)-benzamide 
• 141-43-5 ethanolamine 
• 7646-66-4 N-benzoylaziridine 
• 613-31-0 9,10-dihydroanthracene 
• 33388-23-7 3-benzoyl-2(3H)-benzoxazolethione 
• 3277-27-8 diethyl benzoylphosphonate 
• 22950-57-8 diisopropyl benzoylphosphonate 
• 2902-69-4 2,2,2-trichloroacetophenone 
• 17688-44-7 S-(benzoxazol-2-yl) thiobenzolate 
• 591-50-4 iodobenzene 

Downstream Products

• 66867-07-0 2-phenyl-2,5-dihydrothiazole 
• 18838-10-3 N-(2-hydroxyethyl)-benzamide 
• 7127-19-7 2-phenyl-1,3-oxazoline 
• 36926-15-5 N-(2-hydroxyethyl)benzothioamide 
• 2722-34-1 2-phenylthiazoline 

Relevant articles and documents

Microwave-Assisted Synthesis of 2-Substituted 2-Thiazolines and 5,6-Dihydro-4 H -1,3-thiazines

An efficient and general method for the synthesis of 2-substituted thiazolines and 5,6-dihydro-4 H -1,3-thiazines is developed via microwave-assisted ring closure of ω-thioamidoalcohols promoted by ethyl polyphosphate (PPE). The cyclization reaction involves an S N 2-type mechanism and features the advantages of very short reaction times, high yields and a predictable stereochemical outcome. The acyclic precursors are prepared in high overall yields by an improved diacylation-thionation-saponification sequence from commercially available ω-amino alcohols. The whole process is metal-free and operationally simple.

Imidazole-catalyzed monoacylation of symmetrical diamines

Figure Presented. An imidazole-catalyzed protocol for monoacylation of symmetrical diamines has been developed. The protocol gave selective monoacylation of aliphatic (cyclic and acyclic) primary and secondary diamines. In the reaction, imidazole acts as both catalyst and a leaving group. Different monoacylated piperazines and other diamines were synthesized at room temperature in an ethanol/water solvent system.

Kinetic resolution of vic-amino alcohols catalyzed by a chiral Cu(II) complex

Kinetic resolution of N-benzoylated vic-amino alcohols was achieved by benzoylation in the presence of copper triflate and (R,R)-Ph-BOX as catalysts. The observed enantioselectivity was moderate to high. The method was applied to a kinetic resolution of r