161828-21-3Relevant articles and documents
Diastereoselective synthesis of N-protected β-Amino-α-hydroxyacids (norstatines) from urethane N-carboxyanhydrides (UNCAs)
Audin, Patrick,Pothion, Catherine,Fehrentz, Jean-Alain,Loffet, Andre,Martinez, Jean,Paris, Joelle
, p. 282 - 283 (1999)
β-Amino-α-hydroxyacids (norstatines) are prepared from urethane N- protected carboxyanhydrides (UNCAs); the key step is the diastereoselective reduction of a keto-acetylenic compound, which lead is, with syn diastereoselectivity, to the corresponding prop