1619256-44-8Relevant articles and documents
Palladium catalyzed intramolecular acylcyanation of alkenes using α-iminonitriles
Rondla, Naveen R.,Ogilvie, Jodi M.,Pan, Zhongda,Douglas, Christopher J.
supporting information, p. 8974 - 8977 (2014/08/05)
Reported here is a palladium catalyzed intramolecular acylcyanation of alkenes using α-iminonitriles. Through this method, highly functionalized indanones are synthesized in moderate to high yields using Pd(PPh 3)4, without need for any additional ligands, and a common Lewis acid (ZnCl2). Additionally, the reaction tolerates substitution at various positions on the aromatic ring including electron donating and electron withdrawing groups. This journal is the Partner Organisations 2014.