161982-62-3 Usage
Description
Depreotide, a synthetic peptide, is a somatostatin analog that functions as a potent inhibitor of the release of growth hormone and thyroid-stimulating hormone. It is designed to target and bind to somatostatin receptors, which are often overexpressed in various types of tumors. This property makes it a valuable tool in the field of medical diagnostics and therapeutics.
Uses
Used in Diagnostic Applications:
Depreotide is used as a diagnostic aid in nuclear medicine imaging. It aids in the detection and localization of somatostatin receptor-expressing tumors by binding to these receptors and allowing for the visualization of the tumor's presence and extent.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Depreotide is utilized as a therapeutic agent for the treatment of certain conditions related to the endocrine system. Its ability to inhibit the release of growth hormone and thyroid-stimulating hormone makes it a potential candidate for the management of acromegaly and thyroid eye disease.
Used in Oncology:
Depreotide is also used in oncology for the targeting of tumors that overexpress somatostatin receptors. Its high affinity for these receptors allows for the potential development of targeted therapies, which could improve treatment outcomes and reduce side effects for patients with various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 161982-62-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,9,8 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 161982-62:
(8*1)+(7*6)+(6*1)+(5*9)+(4*8)+(3*2)+(2*6)+(1*2)=153
153 % 10 = 3
So 161982-62-3 is a valid CAS Registry Number.
InChI:InChI=1/C65H96N16O12S2/c1-38(2)55-64(92)76-49(26-30-95-37-54(83)72-35-44(69)57(85)74-47(20-10-13-28-67)58(86)79-52(36-94)62(90)73-46(56(70)84)19-9-12-27-66)65(93)81(3)53(32-39-15-5-4-6-16-39)63(91)78-50(31-40-22-24-42(82)25-23-40)60(88)77-51(33-41-34-71-45-18-8-7-17-43(41)45)61(89)75-48(59(87)80-55)21-11-14-29-68/h4-8,15-18,22-25,34,38,44,46-53,55,71,82,94H,9-14,19-21,26-33,35-37,66-69H2,1-3H3,(H2,70,84)(H,72,83)(H,73,90)(H,74,85)(H,75,89)(H,76,92)(H,77,88)(H,78,91)(H,79,86)(H,80,87)/t44-,46-,47-,48-,49-,50-,51+,52-,53-,55-/m0/s1
161982-62-3Relevant articles and documents
Somatostatin receptor-binding peptides labeled with technetium-99m: Chemistry and initial biological studies
Pearson, Daniel A.,Lister-James, John,McBride, William J.,Wilson, David M.,Martel, Lawrence J.,Civitello, Edgar R.,Taylor, John E.,Moyer, Brian R.,Dean, Richard T.
, p. 1361 - 1371 (2007/10/03)
The synthesis of peptides which possess a high affinity for the somatostatin receptor and contain a chelator for the radionuclide technetium- 99m is described. The target compounds were designed such that they would form stable, oxotechnetium(V) chelate c
