1620-71-9 Usage
Description
CHEMPACIFIC 38184, also known as 5-Methyl-2-(trifluoromethyl)pyridine, is a pyridine-based building block derived from chemical synthesis. It possesses unique structural properties that make it a valuable component in the development of various chemical compounds and materials.
Uses
Used in Chemical Synthesis:
CHEMPACIFIC 38184 is used as a building block for chemical synthesis, particularly in the development of new compounds and materials. Its unique structural properties allow for the creation of a wide range of products with diverse applications across various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, CHEMPACIFIC 38184 is used as an intermediate in the synthesis of various drugs and drug candidates. Its unique properties enable the development of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Agrochemical Industry:
CHEMPACIFIC 38184 is also utilized in the agrochemical industry as a key component in the development of new pesticides, herbicides, and other agricultural chemicals. Its incorporation into these products can enhance their effectiveness and selectivity, leading to improved crop protection and yield.
Used in Material Science:
In the field of material science, CHEMPACIFIC 38184 is employed in the development of advanced materials with specific properties, such as high thermal stability, chemical resistance, or electrical conductivity. These materials can be used in various applications, including electronics, aerospace, and automotive industries.
Used in Research and Development:
CHEMPACIFIC 38184 is also used in research and development laboratories for the exploration of new chemical reactions, synthesis methods, and potential applications. Its unique properties make it an attractive candidate for further investigation and development in various scientific and industrial fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1620-71-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,2 and 0 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1620-71:
(6*1)+(5*6)+(4*2)+(3*0)+(2*7)+(1*1)=59
59 % 10 = 9
So 1620-71-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H6F3N/c1-5-2-3-6(11-4-5)7(8,9)10/h2-4H,1H3
1620-71-9Relevant articles and documents
Trifluoromethylation of aryl and heteroaryl halides with fluoroform-derived CuCF3: Scope, limitations, and mechanistic features
Lishchynskyi, Anton,Novikov, Maxim A.,Martin, Eddy,Escudero-Adan, Eduardo C.,Novak, Petr,Grushin, Vladimir V.
, p. 11126 - 11146 (2013/12/04)
Fluoroform-derived CuCF3 recently discovered in our group exhibits remarkably high reactivity toward aryl and heteroaryl halides, performing best in the absence of extra ligands. A broad variety of iodoarenes undergo smooth trifluoromethylation with the ligandless CuCF3 at 23-50 C to give the corresponding benzotrifluorides in nearly quantitative yield. A number of much less reactive aromatic bromides also have been trifluoromethylated, including pyridine, pyrimidine, pyrazine, and thiazole derivatives as well as aryl bromides bearing electron-withdrawing groups and/or ortho substituents. Only the most electrophilic chloroarenes can be trifluoromethylated, e.g., 2-chloronicotinic acid. Exceptionally high chemoselectivity of the reactions (no side-formation of arenes, biaryls, and C2F5 derivatives) has allowed for the isolation of a large number of trifluoromethylated products in high yield on a gram scale (up to 20 mmol). The CuCF3 reagent is destabilized by CuX coproduced in the reaction, the magnitude of the effect paralleling the Lewis acidity of CuX: CuCl > CuBr > CuI. While SNAr and SRN1 mechanisms are not operational, there is a well-pronounced ortho effect, i.e., the enhanced reactivity of ortho-substituted aryl halides 2-RC6H4X toward CuCF3. Intriguingly, this ortho-effect is observed for R = NO2, COOH, CHO, COOEt, COCH3, OCH3, and even CH3, but not for R = CN. The fluoroform-derived CuCF3 reagent and its reactions with haloarenes provide an unmatched combination of reactivity, selectivity, and low cost.