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1620084-68-5

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1620084-68-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1620084-68-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,2,0,0,8 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1620084-68:
(9*1)+(8*6)+(7*2)+(6*0)+(5*0)+(4*8)+(3*4)+(2*6)+(1*8)=135
135 % 10 = 5
So 1620084-68-5 is a valid CAS Registry Number.

1620084-68-5Relevant articles and documents

Cut and sew: Benzofuran-ring-opening enabled cyclopentenone ring formation

Wang, Kai,Jiang, Chenghao,Zhang, Zhenming,Han, Chunyu,Wang, Xuewei,Li, Yaping,Chen, Kaiting,Zhao, Junfeng

supporting information, p. 12817 - 12820 (2020/11/02)

A facile approach to the fully substituted cyclopentenones involving an unprecedented benzofuran-ring-opening is described. The cleavage of a benzofuran endocyclic C2-O bond proceeded smoothly in the absence of any transition metal catalyst or highly reactive organometallic reagent. Such benzofuran-ring-opening is delicately incorporated into an acid-catalyzed cascade process, orchestrating a novel synthetic strategy for complex cyclopentenones with excellent yields and diastereoselectivities. This journal is

Synthesis of 11C-labeled retinoic acid, [11C]ATRA, via an alkenylboron precursor by Pd(0)-mediated rapid C-[11C] methylation

Suzuki, Masaaki,Takashima-Hirano, Misato,Ishii, Hideki,Watanabe, Chika,Sumi, Kengo,Koyama, Hiroko,Doi, Hisashi

supporting information, p. 3622 - 3625 (2014/07/22)

Retinoids are a class of chemical compounds which include both natural dietary vitamin A (retinol) metabolites and active synthetic analogs. Both experimental and clinical studies have revealed that retinoids regulate a wide variety of essential biological processes. In this study, we synthesized 11C-labeled all-trans-retinoic acid (ATRA), the most potent biologically active metabolite of retinol and used in the treatment of acute promyelocytic leukemia. The synthesis of 11C-labeled ATRA was accomplished by a combination of rapid Pd(0)-mediated C-[11C] methylation of the corresponding pinacol borate precursor prepared by 8 steps and hydrolysis. [11C]ATRA will prove useful as a PET imaging agent, particularly for elucidating the improved therapeutic activity of ATRA (natural retinoid) for acute promyelocytic leukemia by comparing with the corresponding PET probe [11C]Tamibarotene (artificial retinoid).

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