1620580-03-1

Basic information

• Product Name: 2-((2-bromophenyl)amino)-5-methylcyclohexa-2,5-diene-1,4-dione
• Synonyms: 2-((2-bromophenyl)amino)-5-methylcyclohexa-2,5-diene-1,4-dione
• CAS NO: 1620580-03-1
• Molecular Weight: 292.132
• Mol File: 1620580-03-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-((2-bromophenyl)amino)-5-methylcyclohexa-2,5-diene-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((2-bromophenyl)amino)-5-methylcyclohexa-2,5-diene-1,4-dione(1620580-03-1)
• EPA Substance Registry System: 2-((2-bromophenyl)amino)-5-methylcyclohexa-2,5-diene-1,4-dione(1620580-03-1)

Safety Data

• Hazardous Substances Data: 1620580-03-1(Hazardous Substances Data)

Upstream product

• 1620579-95-4 4-((2-bromophenyl)amino)-2,5-dimethoxybenzaldehyde 
• 90064-47-4 4-iodo-2,5-dimethoxybenzenecarbaldehyde 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 1620580-02-0 N-(2-bromophenyl)-2,5-dimethoxy-4-methylaniline 

Downstream Products

• 100108-66-5 murrayaquinone A 

Relevant articles and documents

Palladium mediated intramolecular multiple C-X/C-H cross coupling and C-H activation: Synthesis of carbazole alkaloids calothrixin B and murrayaquinone A

Straightforward palladium mediated syntheses of calothrixin B and murrayaquinone A are described. Regioselective palladium mediated intramolecular multiple C-X/C-H cross coupling reaction on N-(4-((2-bromophenyl)amino)-2,5- dimethoxybenzyl)-N-(2-iodophenyl)acetamide followed by CAN oxidation afforded calothrixin B in excellent yield in two steps. A linear synthesis has also been developed for calothrixin B. Utilizing C-H functionalization as well as palladium mediated intramolecular C-X/C-H cross coupling reaction, murrayaquinone A synthesis was achieved. Overall, these synthetic methodologies provide an expedient entry to these biologically active alkaloids in a short reaction sequence. This journal is the Partner Organisations 2014.