1621585-77-0

Basic information

• Product Name: (4aR,6R,8aS)-2-(benzoylamino)-8a-(2,4-difluorophenyl)-N-(4-hydroxypyridin-3-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazine-6-carboxamide
• Synonyms: (4aR,6R,8aS)-2-(benzoylamino)-8a-(2,4-difluorophenyl)-N-(4-hydroxypyridin-3-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazine-6-carboxamide
• CAS NO: 1621585-77-0
• Molecular Weight: 524.548
• Mol File: 1621585-77-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4aR,6R,8aS)-2-(benzoylamino)-8a-(2,4-difluorophenyl)-N-(4-hydroxypyridin-3-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazine-6-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (4aR,6R,8aS)-2-(benzoylamino)-8a-(2,4-difluorophenyl)-N-(4-hydroxypyridin-3-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazine-6-carboxamide(1621585-77-0)
• EPA Substance Registry System: (4aR,6R,8aS)-2-(benzoylamino)-8a-(2,4-difluorophenyl)-N-(4-hydroxypyridin-3-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazine-6-carboxamide(1621585-77-0)

Safety Data

• Hazardous Substances Data: 1621585-77-0(Hazardous Substances Data)

Upstream product

• 1425947-62-1 [(2R,4R,5S)-5-amino-2-[(benzyloxy)methyl]-5-(2,4-difluorophenyl)tetrahydro-2H-pyran-4-yl]methanol 
• 1425947-61-0 (3aR,5R,7aS)-5-[(benzyloxy)methyl]-7a-(2,4-difluorophenyl)hexahydro-1H-pyrano[3,4-c][1,2]oxazole 
• 6320-39-4 3-aminopyridin-4-ol 
• 1220328-97-1 (3aR,5R)-5-[(benzyloxy)methyl]-3,3a,4,5-tetrahydro-7H-pyrano[3,4-c][1,2]oxazole 
• 1220328-95-9 2-{[(2R)-1-(benzyloxy)pent-4-en-2-yl]oxy}-N-hydroxyethanimine 
• 1220328-94-8 ({[(2R)-2-(2,2-diethoxyethoxy)pent-4-en-1-yl]oxy}methyl)benzene 
• 58931-16-1 (R)-1-benzyloxypent-4-en-2-ol 

Downstream Products

• 1621585-78-1 N-[(4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-([1,3]oxazolo[4,5-c]pyridin-2-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-yl]benzamide 
• 1621585-18-9 (4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-([1,3]oxazolo[4,5-c]pyridin-2-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine 

Relevant articles and documents

Heteroaryl-Substituted Hexahydropyrano[3,4-d][1,3]Thiazin-2-Amine Compounds

The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula I, and the variables R1 and R2 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.