16232-91-0 Usage
Description
(2R)-2,3-Dihydroxypropyl-b-D-galactopyranoside, also known as (2R)-Glycerol-O-β-D-galactopyranoside (RGG), is a naturally occurring disaccharide derivative that plays a significant role in various biological processes and applications. It is a substrate for several enzymes and systems, including β-galactosidase, the lactose repressor, the galactose-binding protein, and the β-methylgalactoside transport system. RGG also serves as a substrate for the third lac operon encoded enzyme, thiogalactoside transacetylase.
Uses
Used in Molecular Biology and Genetics:
(2R)-2,3-Dihydroxypropyl-b-D-galactopyranoside is used as a research tool for studying the function and regulation of the lac operon in E. coli. It serves as a substrate for the third lac operon encoded enzyme, thiogalactoside transacetylase, which aids in understanding the genetic control of lactose metabolism and the regulation of gene expression in bacteria.
Used in Enzyme Assays and Screening:
(2R)-2,3-Dihydroxypropyl-b-D-galactopyranoside is used as a substrate in enzyme assays to study the activity and specificity of β-galactosidase, an enzyme that plays a crucial role in the breakdown of lactose. This application is essential for the development of new drugs targeting β-galactosidase-related diseases and for screening potential inhibitors or activators of the enzyme.
Used in Drug Delivery Systems:
(2R)-2,3-Dihydroxypropyl-b-D-galactopyranoside can be used as a component in the development of targeted drug delivery systems, particularly for cancer therapy. Its ability to serve as a substrate for various enzymes and systems in E. coli makes it a promising candidate for the design of novel drug carriers that can specifically target cancer cells while minimizing side effects on healthy cells.
Used in Analytical Chemistry:
(2R)-2,3-Dihydroxypropyl-b-D-galactopyranoside can be employed as a reference compound in the development and validation of analytical methods for the detection and quantification of related compounds in various samples, such as food, pharmaceuticals, and biological fluids. This application is crucial for ensuring the quality, safety, and efficacy of products containing these compounds.
Used in the Food Industry:
(2R)-2,3-Dihydroxypropyl-b-D-galactopyranoside can be used as a component in the development of novel food products with enhanced nutritional properties, such as prebiotics or functional foods. Its ability to serve as a substrate for various enzymes and systems in E. coli may contribute to the development of products that promote gut health and overall well-being.
Check Digit Verification of cas no
The CAS Registry Mumber 16232-91-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,3 and 2 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 16232-91:
(7*1)+(6*6)+(5*2)+(4*3)+(3*2)+(2*9)+(1*1)=90
90 % 10 = 0
So 16232-91-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H18O8/c10-1-4(12)3-16-9-8(15)7(14)6(13)5(2-11)17-9/h4-15H,1-3H2/t4-,5?,6+,7+,8?,9-/m1/s1
16232-91-0Relevant articles and documents
Cerebrosides and a monoacylmonogalactosylglycerol from Clinacanthus nutans
Tuntiwachwuttikul, Pittaya,Pootaeng-On, Yupa,Phansa, Photchana,Taylor, Walter Charles
, p. 27 - 32 (2004)
A mixture of nine cerebrosides and a monoacylmonogalactosylglycerol were seperated from the leaves of Clinacanthus nutans. The structures of the cerebrosides were characterized as 1-O-β-D-glucosides of phytosphingosines, which comprised a common long-chain base, (2S,3S,4R,8Z)-2-amino-8(Z)- octadecene-1,3,4-triol with nine 2-hydroxy fatty acids of varying chain lengths (C16, C18, C20-26) linked to the amino group. The glycosylglyceride was characterized as (2S)-1-O-linolenoyl-3-O-β-D- galactopyranosylglycerol. The structures were established on the basis of the spectroscopic data and chemical reactions.
Secondary metabolites from the leaves of Feijoa sellowiana Berg.
Ruberto, Giuseppe,Tringali, Corrado
, p. 2947 - 2951 (2004)
The investigation of the lipid extract of leaves of Feijoa sellowiana cultivated along the east coast of Sicily has yielded in addition to the widespread secondary metabolites: α-tocopherol, flavone, stigmasterol and β-carotene, an inseparable mixture of tyrosol esters of lignoceric (1a), cerotic (1b) and montanic (1c) acids, and a novel galactolipid identified as (2S)-1,2,6′-tri-O-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl] -3-O-β-d-galactopyranosyl glycerol (2).
Arabidopsides A and B, two new oxylipins from Arabidopsis thaliana
Hisamatsu, Yosuke,Goto, Nobuharu,Hasegawa, Koji,Shigemori, Hideyuki
, p. 5553 - 5556 (2003)
Two new oxylipins, arabidopsides A (1) and B (2), were isolated from the aerial parts of Arabidopsis thaliana, and their structures and absolute stereochemistries were elucidated by spectroscopic data and chemical means. Arabidopsides A (1) and B (2) were rare monogalactosyl diacylglycerides containing 12-oxophytodienoic acid and/or dinor-oxophytodienoic acid.
Apoptosis-inducing galactolipids from a cultured marine diatom, Phaeodactylum tricornutum
Andrianasolo, Eric H.,Haramaty, Liti,Vardi, Assaf,White, Eileen,Lutz, Richard,Falkowski, Paul
experimental part, p. 1197 - 1201 (2009/11/30)
Two monogalactosyl diacylglycerols, 1 and 2, were isolated from the marine diatom Phaeodactylum tricornutum, using the patented ApopScreen cell-based screen for apoptosis-inducing, potential anticancer compounds. The molecular structures of the galactolipids were determined using a combination of NMR, mass spectrometry, and chemical degradation. The bioactivities were confirmed using a specific apoptosis induction assay based on genetically engineered mammalian cell lines with differential, defined capacities for apoptosis. The galactolipids induce apoptosis in micromolar concentrations. This is the first report of apoptosis induction by galactolipids.
