16240-00-9 Usage
Description
(2Z)-3-(2-methylphenyl)-2-[(2-methylphenyl)imino]-1,3-thiazolidin-4-one, also known as thiazolidin-4-one, is a heterocyclic compound characterized by a thiazolidine ring. It is a thiazolidinone derivative with a molecular formula of C15H15NOS. Thiazolidin-4-one has been the subject of research for its potential pharmacological properties, including anti-inflammatory, anticancer, and antimicrobial activities. It has been utilized in medicinal chemistry for the development of new drugs and pharmaceuticals, and its derivatives have also been investigated for antioxidant and antidiabetic properties. However, more research is necessary to fully comprehend the biological activities and potential applications of this compound.
Uses
Used in Pharmaceutical Industry:
(2Z)-3-(2-methylphenyl)-2-[(2-methylphenyl)imino]-1,3-thiazolidin-4-one is used as a pharmaceutical agent for its potential anti-inflammatory properties, offering a therapeutic option for treating inflammation-related conditions.
(2Z)-3-(2-methylphenyl)-2-[(2-methylphenyl)imino]-1,3-thiazolidin-4-one is used as an anticancer agent, targeting various types of cancer cells and potentially serving as a novel therapeutic approach in oncology.
(2Z)-3-(2-methylphenyl)-2-[(2-methylphenyl)imino]-1,3-thiazolidin-4-one is used as an antimicrobial agent, providing an alternative for combating microbial infections and contributing to the development of new antibiotics.
Used in Medicinal Chemistry Research:
(2Z)-3-(2-methylphenyl)-2-[(2-methylphenyl)imino]-1,3-thiazolidin-4-one is used as a research compound for the development of new drugs, given its promising pharmacological properties and potential applications in various therapeutic areas.
(2Z)-3-(2-methylphenyl)-2-[(2-methylphenyl)imino]-1,3-thiazolidin-4-one is used as a starting material for the synthesis of thiazolidin-4-one derivatives, which are being investigated for their antioxidant and antidiabetic properties, expanding the scope of its potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 16240-00-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,4 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 16240-00:
(7*1)+(6*6)+(5*2)+(4*4)+(3*0)+(2*0)+(1*0)=69
69 % 10 = 9
So 16240-00-9 is a valid CAS Registry Number.
16240-00-9Relevant articles and documents
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Bhargava
, p. 51 (1951)
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Thiazolidione derivatives as novel antibiofilm agents: Design, synthesis, biological evaluation, and structure-activity relationships
Pan, Bin,Huang, Renzheng,Zheng, Likang,Chen, Chen,Han, Shiqing,Qu, Di,Zhu, Mingli,Wei, Ping
scheme or table, p. 819 - 824 (2011/04/16)
Rational designed novel thiazolidiones were synthesized and evaluated for antibiofilm activity. The active derivatives were not only potent inhibitors of Staphylococcus epidermidis biofilm growth but also efficient antibacterial agents. 3f showed 4-fold higher activity (6.25 μM) in the biofilms dispersal assay and significantly higher antibacterial activity (MIC 3.125 μM) in comparison to the 3-(5-((6- (ethoxycarbonyl)-5-(benzo[1,3]dioxol-5-yl)-3-oxo-7- phenyl- thiazolo[3,2-a]pyrimidin-2(5H)-ylidene)methyl)furan-2-yl)benzoic acid (1).
Axially chiral 2-arylimino-3-aryl-thiazolidine-4-one derivatives: Enantiomeric separation and determination of racemization barriers by chiral HPLC
Erol, Sule,Dogan, Ilknur
, p. 2494 - 2500 (2008/02/02)
Axially chiral 2-arylimino-3-aryl-thiazolidine-4-ones have been synthesized as racemic mixtures, and each mixture with the exception of 2-(o-chlorophenyl)imino-3-(o-chlorophenyl)-thiazolidine-4-one has been converted to the corresponding 5-benzylidene-2-a
