162611-38-3

Basic information

• Product Name: O-(5'-O-(4,4'-dimethoxytrityl)-N⁶-benzoyl-2-deoxyadenosin-3'-yl) N,N-diisopropylfluorophosphoramidite
• CAS NO: 162611-38-3
• Molecular Weight: 806.874
• Mol File: 162611-38-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: O-(5'-O-(4,4'-dimethoxytrityl)-N⁶-benzoyl-2-deoxyadenosin-3'-yl) N,N-diisopropylfluorophosphoramidite(CAS DataBase Reference)
• NIST Chemistry Reference: O-(5'-O-(4,4'-dimethoxytrityl)-N⁶-benzoyl-2-deoxyadenosin-3'-yl) N,N-diisopropylfluorophosphoramidite(162611-38-3)
• EPA Substance Registry System: O-(5'-O-(4,4'-dimethoxytrityl)-N⁶-benzoyl-2-deoxyadenosin-3'-yl) N,N-diisopropylfluorophosphoramidite(162611-38-3)

Safety Data

• Hazardous Substances Data: 162611-38-3(Hazardous Substances Data)

Upstream product

• 921-27-7 di(isopropyl)aminodifluorophosphane 
• 64325-78-6 N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine 
• 162611-32-7 O-(5'-O-(4,4'-dimethoxytrityl)-N⁶-benzoyl-2-deoxyadenosin-3'-yl) O-(4-nitrophenyl) N,N-diisopropylphosphoramidite 
• 921-26-6 N,N-diisopropylphosphoramide dichloride 
• 153413-65-1 O,O'-bis-(4-nitrophenyl) N,N-diisopropylphosphoramidite 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 4546-72-9 N₆-benzoyl-2'-deoxyadenosine 
• 162611-31-6 4-nitrophenyl-N,N-diisopropylchlorophosphoramidite 

Downstream Products

• 171233-70-8 N⁶-Benzoyl-5'-O-DMTr-2'-deoxyadenosine (3'-5')-3'-O-DMTr-thymidine phosphorfluoridite 
• 171081-11-1 O-(5'-O-(4,4'-dimethoxytrityl)-N⁶-benzoyl-2-deoxyadenosin-3'-yl) O-(tert-butyl) phosphorofluoridite 
• 171081-21-3 Thiophosphorofluoridic acid O-{(2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester O'-(2-cyano-ethyl) ester 
• 171081-17-7 Phosphorofluoridic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester 
• 171081-18-8 O-(5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl) O-(tert-butyl) thiophosphorofluoridate 
• 182370-37-2 O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] hydrogen thiophosphorofluoridate 
• 171081-19-9 O-(5'-O-(4,4'-dimethoxytrityl)-N⁶-benzoyl-2-deoxyadenosin-3'-yl) O-(tert-butyl) thiophosphorofluoridate 
• 171081-15-5 O-(5'-O-(4,4'-dimethoxytrityl)-N⁶-benzoyl-2-deoxyadenosin-3'-yl) O-(tert-butyl) phosphorofluoridate 
• 171081-13-3 Phosphorofluoridous acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester 

Relevant articles and documents

Synthesis of phosphorofluoridates and phosphorofluoridothioates via the phosphoramidite approach

We present a very efficient synthetic procedure leading to the phosphorofluoridates RO-P(O)(OH)F 1 or phosphorofluoridothioates RO-P(S)(OH)F 2, which is based on the intermediary of fluorophosphoramidites (RO)P(F)N iPr2 5 [R = 9-(hyd

Synthesis of 2'-Deoxynucleosid-3'-yl-N,N-Diisopropylaminophosphorfluoridites. A New Class of Stable PIII Nucleotides Containing a P-F Bond

A new methodology based on phosphitylating reagents containing 4-nitrophenoxy leaving group has been employed to synthesize stable 5'-O-(4,4'-dimethoxytrityl)nucleosid-3'-yl-N,N-diisopropylaminophosphofluoridites 1a-d.