16269-44-6 Usage
Description
(2E)-2-(2-methylbenzylidene)hydrazinecarboxamide is a hydrazine derivative with the molecular formula C9H12N4O. It features a carboxamide functional group and a substituted benzylidene moiety, which may contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
(2E)-2-(2-methylbenzylidene)hydrazinecarboxamide is used as a chemical intermediate for the development of new drugs. Its unique structure and functional groups may offer novel therapeutic properties, making it a promising candidate for further research and synthesis in drug discovery.
Used in Agricultural Industry:
(2E)-2-(2-methylbenzylidene)hydrazinecarboxamide is used as a potential component in the development of new pesticides. Its chemical properties could provide innovative solutions for pest control and contribute to the advancement of agricultural products.
The synthesis and study of (2E)-2-(2-methylbenzylidene)hydrazinecarboxamide's properties could lead to a better understanding of its potential uses and effects, opening up new avenues for its application in both the pharmaceutical and agricultural industries.
Check Digit Verification of cas no
The CAS Registry Mumber 16269-44-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,6 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 16269-44:
(7*1)+(6*6)+(5*2)+(4*6)+(3*9)+(2*4)+(1*4)=116
116 % 10 = 6
So 16269-44-6 is a valid CAS Registry Number.
16269-44-6Relevant articles and documents
Semicarbazone derivatives as urease inhibitors: Synthesis, biological evaluation, molecular docking studies and in-silico ADME evaluation
Qazi, Syeda Uroos,Rahman, Shafiq Ur,Awan, Asia Naz,al-Rashida, Mariya,Alharthy, Rima D.,Asari, Asnuzilawati,Hameed, Abdul,Iqbal, Jamshed
, p. 19 - 26 (2018/05/14)
A series of hydrazinecarboxamide derivatives were synthesized and examined against urease for their inhibitory activity. Among the series, the 1-(3-fluorobenzylidene)semicarbazide (4a) (IC50 = 0.52 ± 0.45 μM), 4u (IC50 = 1.23 ± 0.32 μM) and 4h (IC50 = 2.22 ± 0.32 μM) were found most potent. Furthermore, the molecular docking study was also performed to demonstrate the binding mode of the active hydrazinecarboxamide with the enzyme, urease. In order to estimate drug likeness of compounds, in silico ADME evaluation was carried out. All compounds exhibited favorable ADME profiles with good predicted oral bioavailability.
Synthesis and biological activity of 5-substituted-2-amino-1,3,4-oxadiazole derivatives
Kumar, Sanjeev
experimental part, p. 99 - 108 (2011/11/29)
Electrical energy offers numerous benefits for performing synthesis, including increased reaction rates, enhanced yields, and cleaner chemistries. 5-Substituted-2-amino-1,3,4-oxadiazoles were synthesized directly from the semicarbazone at a platinum elect
