162791-22-2Relevant articles and documents
New products from the reactions of artemisinin with ammonia and amines
Galal, Ahmed M.,Ahmad, M. Shamim,El-Feraly, Farouk S.,McPhail, Andrew T.
, p. 54 - 58 (1999)
Reaction of artemisinin (1) with ammonia, methylamine, dimethylamine, and allylamine afforded five unexpected products 2-6, in addition to the previously reported compounds 7-12. The identities of the new compounds were established from their spectral data, by chemical derivatization and by comparison with published reports. The stereochemistries of compounds 5 and 6 were confirmed by single-crystal X-ray analysis.
