16287-97-1 Usage
Description
4-Chloro-1,7-naphthyridine is a chemical compound belonging to the naphthyridine family of heterocycles. It is characterized by the presence of a chlorine atom at the 4th position and a nitrogen atom at the 1st and 7th positions in the ring structure. 4-Chloro-1,7-naphthyridin... exhibits unique chemical and biological properties, making it a potential candidate for various applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
4-Chloro-1,7-naphthyridine is used as an active pharmaceutical ingredient (API) for the development of drugs targeting cell proliferative disorders. Its chemical structure allows for the modulation of specific biological pathways involved in the regulation of cell growth and proliferation, making it a promising candidate for the treatment of various diseases characterized by abnormal cell growth, such as cancer.
Used in Chemical Synthesis:
In the chemical industry, 4-Chloro-1,7-naphthyridine can be used as a building block or intermediate in the synthesis of more complex molecules with diverse applications. Its unique structure and reactivity enable the development of novel compounds with potential applications in various fields, including materials science, agrochemistry, and pharmaceuticals.
Used in Research and Development:
4-Chloro-1,7-naphthyridine can also be employed as a research tool in the study of biological processes and the development of new therapeutic strategies. Its unique chemical properties make it a valuable compound for investigating the mechanisms underlying cell proliferation and the identification of potential targets for therapeutic intervention.
Check Digit Verification of cas no
The CAS Registry Mumber 16287-97-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,8 and 7 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 16287-97:
(7*1)+(6*6)+(5*2)+(4*8)+(3*7)+(2*9)+(1*7)=131
131 % 10 = 1
So 16287-97-1 is a valid CAS Registry Number.
16287-97-1Relevant articles and documents
ARYL LINKED IMIDAZOLE AND TRIAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR IMPROVING THE PHARMACOKINETICS OF A DRUG
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Page/Page column 96, (2015/06/03)
The present invention relates to aryl linked imidazole and triazole derivatives, compositions comprising said compounds, alone or in combination with other drugs, and methods of using the compounds for improving the pharmacokinetics of a drug. The compounds of the invention are useful in human and veterinary medicine for inhbiting CYP3A4 and for improving the pharmacokinetics of a therapeutic compound that is metabolized by CYP3A4.
2,4-DIARYL - SUBSTITUTED [1,8] NAPHTHYRIDINES AS KINASE INHIBITORS FOR USE AGAINST CANCER
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Paragraph 0504, (2013/05/08)
The present invention relates to novel [1,8]naphthyridine derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particu
NAPHTHYRIDINE DERIVATIVES
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Page/Page column 137, (2010/11/28)
The invention concerns naphthyridine derivatives of Formula (Ia) or (Ib) or a pharmaceutically-acceptable salt thereof, wherein each of X1, p, R1, G1, G2, q, R2, R3, R4, R5, Ring A, r and R6 has any of the meanings defined hereinbefore in the description; pharmaceutical compositions containing them and their use in the treatment of cell proliferative disorders or disease states associated with angiogenesis and/or vascular permeability.